Dr. Sessa Discusses ATR Inhibitors in BRCA-Mutated Tumors
November 8th 2017Cristiana Sessa, MD, head of Phase I-II Unit and Pharmacology, vice head of Medical Oncology and Head of Clinical Research, Oncology Institute of Southern Switzerland, discusses ataxia–telangiectasia and Rad3 related (ATR) inhibitors in patients with ovarian cancer who have BRCA-mutated tumors.
Dr. Bosch on the HPV Vaccination in the Prevention of Cervical Cancer
November 8th 2017Xavier Bosch, MD, MPH, Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d' Oncologia–Catalan Institute of Oncology, introduces a second-generation vaccination against the human papilloma virus (HPV) for the prevention of cervical cancer.
Survey Shows Patients Consider Several Factors of Maintenance Therapy for Ovarian Cancer Treatment
November 8th 2017Patients with ovarian cancer were unified in their responses regardless of age, disease stage, or whether they had primary or recurrent disease, and were more likely to opt to receive maintenance therapy if it could offer delay of disease progression and allow patients to maintain or improve their quality of life.
PALB2 Mutation Implicated in Higher Risk of Breast Cancer, Not Ovarian
November 8th 2017Deleterious mutations in the PALB2 gene may account for the development of breast cancer in women with an elevated risk due to a family history of breast or ovarian cancer, but who test negative for the BRCA1 or BRCA2 genes.
Tisotumab Vedotin Shows Clinical Benefit and Ongoing Responses in Cervical Cancer
November 7th 2017A first-in-human study showed that the antibody drug conjugate tisotumab vedotin was well-tolerated and provided promising anti-tumor activity in patients with relapsed, recurrent, and/or metastatic cervical cancer.
No Overall Survival Advantage in Frontline Nintedanib With Chemotherapy in Advanced Ovarian Cancer
November 7th 2017The final analysis of overall survival data from the phase III AGO-OVAR 12 trial of nintedanib plus carboplatin/paclitaxel versus carboplatin/paclitaxel alone in women with chemotherapy-naive advanced ovarian cancer did not demonstrate a survival advantage with the addition of nintedanib.
Salvage Surgery Improved PFS in Platinum-Sensitive Recurrent Ovarian Cancer
November 7th 2017Patients with relapsed ovarian cancer and a positive Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) score experienced prolonged progression-free survival after undergoing a second cytoreductive surgery followed by platinum-based chemotherapy.
Dr. Mahantshetty Discusses Results of Chemoradiation in Cervical Cancer
November 7th 2017Umesh Mahantshetty, MD, MBBS, radiation oncologist, Tata Memorial Hospital, Mumbai, discusses the results of a trial of chemoradiation in patients with cervical cancer, presented at the 2017 International Meeting of the European Society of Gynaecological Oncology (ESGO).
Dr. Sehouli Discusses Trial of Secondary Cytoreductive Surgery in Ovarian Cancer
November 7th 2017Jalid Sehouli, MD, professor, director of the Clinic Campus Virchow and Campus Benjamin Franklin Charité Center Gynecology, Charité – Universitatsmedizin Berlin, discusses a trial of secondary cytoreductive surgery in patients with ovarian cancer, presented at the 2017 International Meeting of the European Society of Gynaecological Oncology (ESGO).