Video

Dr. Levy on Repeat Testing in NSCLC

Benjamin P. Levy, MD, discusses the importance of repeat testing in non–small cell lung cancer.

Benjamin P. Levy, MD, assistant professor of oncology and clinical director of Medical Oncology, Sidney Kimmel Cancer Center, Johns Hopkins Medicine, discusses the importance of repeat testing in non—small cell lung cancer (NSCLC).

Repeat testing at diagnosis is important for patients whose initial tissue or liquid biopsy was inconclusive, says Levy. An inconclusive liquid biopsy may indicate a patient is not shedding circulating tumor DNA, says Levy. In these cases, repeat testing may reveal a genetic mutation.

Patients who develop resistance to a therapy should also be considered for repeat testing, says Levy.

Additionally, patients who progress on genotype-directed therapies like osimertinib (Tagrisso) or alectinib (Alecensa) should be considered for repeat testing as it can help optimize subsequent therapy for these patients, concludes Levy.

Related Videos
Viktor Grünwald, MD, PhD
Aaron Gerds, MD
Christine M. Lovly, MD, PhD, Ingram Associate Professor of Cancer Research, associate professor, medicine (hematology/oncology), Vanderbilt-Ingram Cancer Center
Haeseong Park, MD, MPH
David L. Porter, MD
Timothy Yap, MBBS, PhD, FRCP
Leo I. Gordon, MD, Abby and John Friend Professor of Oncology Research, professor, medicine (hematology and oncology), Feinberg School of Medicine, Robert H. Lurie Cancer Center
Hetty E. Carraway, MD, MBA, staff associate professor, Department of Medicine, School of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University; member, Immune Oncology Program, Case Comprehensive Cancer Center; vice chair, Strategy and Enterprise Development, Taussig Cancer Institute, Division of Hematologic Oncology and Blood Disorders, Cleveland Clinic
David A. Braun, MD, PhD, assistant professor, medicine (medical oncology), Louis Goodman and Alfred Gilman Yale Scholar, member, Center of Molecular and Cellular Oncology, Yale Cancer Center
Julia Foldi, MD, PhD