Iomab-B Shows Promise as Novel Conditioning for HSCT in AML
February 25th 2019More than 90% of older patients with relapsed/refractory acute myeloid leukemia had successful engraftment of allogeneic hematopoietic stem cell transplant preceded by novel conditioning with an iodinated CD45-targeted antibody.
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Herpes Zoster Vaccine Elicits Robust Immune Response in HSCT Patients
February 25th 2019Two doses of adjuvanted recombinant zoster vaccine following autologous hematopoietic stem cell transplant led to rapid and durable cell-mediated immune responses, results from a subgroup analysis of a large randomized, placebo-controlled trial showed.1
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City of Hope Awarded Lymphoma SPORE Grant From NCI
February 22nd 2019An international leader in finding new, innovative treatments for lymphoma patients, City of Hope announced today that it has received its third lymphoma Specialized Programs of Research Excellence grant from the National Cancer Institute.
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Pretransplant MRD Prognostic for Outcomes in Adults With ALL
February 22nd 2019Adults with acute lymphoblastic leukemia had worse outcomes, including lower survival, after myeloablative allogeneic transplantation if they remained positive for minimal residual disease at the time of transplant.
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Research Finds Rivaroxaban Significantly Reduces Blood Clots in Patients With Cancer
February 21st 2019Cleveland Clinic research has found that the blood thinner rivaroxaban significantly reduces venous thromboembolism (VTE)—a blood clot in the venous system—and VTE-related death for outpatient, high-risk cancer patients while they are taking the oral anticoagulant.
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NCCN Guidelines Reflect Recent FDA Approvals for Hematologic Malignancies
February 13th 2019New options for patients with hematologic malignancies stemming from recent FDA approvals are making an impact on treatment strategies recommended in the National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology.
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Highlighting Headway Made in NSCLC in New York
February 13th 2019We traveled to New York, New York, for a State of the Science Summit™ on Advanced Non–Small Cell Lung Cancer, which focused on topics ranging from surgical techniques, to headway made in immunotherapy, to emerging biomarkers, to diagnostic advancements.
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Examining Breakthroughs Made in Breast Cancer in Minneapolis
February 7th 2019We traveled to Minneapolis, Minnesota, for a State of the Science Summit on Breast Cancer, which focused on surgical approaches for node-positive breast cancer, the use of CDK4/6 inhibitors in hormone receptor–positive disease, and emerging drug therapies in triple-negative disease.
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Roswell Park Researchers Propose 2 New Strategies for Treating Pancreatic Cancer
February 1st 2019In a pair of new studies, researchers from Roswell Park Comprehensive Cancer Center outline strategies for overcoming pancreatic cancer’s resistance to treatment through approaches that exploit this cancer’s reliance on uncontrolled, or deregulated, cell proliferation.
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JTCC Leading Enrollment for WIZARD Study Evaluating DSP-7888 in Recurrent Glioblastoma
February 1st 2019John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center announced that it is leading enrollment worldwide for WIZARD 201G, a global Phase 2 study in glioblastoma.
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Navigating New Advances Made in NSCLC in New York
January 31st 2019We traveled to Syracuse, New York, for a State of the Science Summit on Advanced Non–Small Cell Lung Cancer, which focused on practice-change clinical trials in the space, as well as novel approaches to treatment with checkpoint inhibitors, targeted therapies, radiation, and minimally invasive surgery.
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Dana-Farber Researchers Win Grand Challenge Funding from Cancer Research UK
January 25th 2019Dana-Farber Cancer Institute researchers are Grand Challenge winners for a project that aims to discover how certain microbes inside the body lead to colorectal cancer and influence a patient’s response to treatment.
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Making Moves in Multiple Myeloma in NYC
January 24th 2019We traveled to New York City, New York, for a State of the Science Summit on Multiple Myeloma, which focused on stem cell transplant, minimal residual disease, maintenance options, and treatment approaches for newly diagnosed myeloma.
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Study Finds Patients With Cancer Are Less Likely to Die of Opioid Overdose
January 22nd 2019Despite changes affecting how oncologists prescribe and manage opioid use among their patients, there are few data analyzing the frequency and extent to which patients with cancer die of opioid overdoses.
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Pembrolizumab/Trastuzumab Induction Highly Active in HER2+ Gastric, GEJ Cancer
January 18th 2019Two-thirds of patients with untreated metastatic HER2-positive esophagogastric adenocarcinoma remained free of disease progression at 6 months with a combination of pembrolizumab, trastuzumab, and chemotherapy.
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ACCC 2018 Survey Finds Multiple Barriers to Cancer Program Growth
January 17th 2019The Association of Community Cancer Centers ninth annual Trending Now in Cancer Care survey reveals how cancer programs across the country are being impacted by pressure from turbulence in multiple sectors: payers, government, and industry.
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Perusing Progress Made in NSCLC in Washington DC
January 16th 2019We traveled to Washington D.C. for a State of the Science Summit on Breast Cancer, which focused on additional recent advances in the NSCLC and small cell lung cancer paradigms, touching on TKIs, immunotherapy, and other investigational agents.
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