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|Videos|January 31, 2022

ASH 2021: Novel Therapy in Acute Lymphocytic Leukemia

Author(s)Matthew S. Davids, MD, MMSc, Dana-Farber Cancer Institute, Jae Park, MD, Memorial Sloan Kettering Cancer Center, Elias J. Jabbour, MD, MD Anderson

Expert perspectives on clinical data readouts in acute lymphocytic leukemia from the ASH 2021 annual meeting.

Episodes in this series

Expert on Leukemia

EP. 1 ASH 2021: Novel Therapy in Acute Lymphocytic Leukemia

Expert on Leukemia

EP. 2 ASH 2021: Key Data in Chronic Myeloid Leukemia

Expert on Leukemia

EP. 3 ASH 2021: Updates in the Chronic Lymphocytic Leukemia Treatment Landscape

Data from the following clinical trials are discussed:

1233: Updated results from a phase I study of hyper-CVAD with sequential blinatumomab in adults with newly diagnosed Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia
1231: Superior overall survival with blinatumomab versus chemotherapy as pre-transplant consolidation treatment in children with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL): longer follow-up (FU) of a phase 3 randomized controlled trial (RCT)
4028: Successful outpatient administration of blinatumomab infusion in pediatric patients with acute lymphoblastic leukemia
516: Isatuximab in combination with chemotherapy in pediatric patients with relapsed/refractory acute lymphoblastic leukemia or acute myeloid leukemia (ISAKIDS): interim analysis
428: Real-world outcomes for pediatric and young adult patients with relapsed refractory (R/R) B-cell acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel: update from the Center for International Blood and Marrow Transplant Research (CIBMTR) Registry

Supported in part by Takeda Oncology. Content developed independently by Onclive®.

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