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OncLive® will be LIVE with OncLive® News Network: On Location at the 2024 ASCO Annual Meeting. Each day, we will broadcast a series of interviews with top thought leaders, to learn their thoughts and reactions to data presented across oncology during the conference.

Sifting Through Data in Lung Cancer and Leukemia: Drs Levy and Saint Fleur

The addition of pelabresib and ruxolitinib (Jakafi) led to a significant and durable reduction in splenomegaly, among other improvements, vs ruxolitinib alone in JAK inhibitor–naive patients with myelofibrosis.

Updated MANIFEST-2 Data With Pelabresib/Ruxolitinib Support Paradigm Shift in Myelofibrosis

Ponatinib generated long-term efficacy and displayed manageable safety in chronic-phase chronic myeloid leukemia harboring a T315I mutation.

Ponatinib Showcases Long-Term Efficacy, Safety in CP-CML With T315I Mutations

Viktor Grünwald, MD, PhD, on patterns of progression and subsequent therapy for patients with advanced RCC treated during the phase 3 CLEAR trial.

Dr Grünwald on Examining Progression Patterns for Lenvatinib Plus Pembrolizumab in Advanced RCC

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The COMBI-AD dataset is the longest follow-up to date of adjuvant treatment for patients with stage III melanoma. 

Up to 10 Years of Follow-Up Uphold Survival Benefit With Adjuvant Dabrafenib/Trametinib in Stage III Melanoma 

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Inside the Clinic: Updates in the Prevention and Treatment of Graft versus Host Disease

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, discuss recent updates in the prophylactic and treatment strategies for acute and chronic graft versus host disease (GVHD).

Sophie Paczesny, MD, PhD, explains which malignancies allogeneic transplantation can be used as a potentially curative treatment approach, and which patients are best suited for transplant.

Indications for Allogeneic Stem Cell Transplantation in the Treatment of Hematological Malignancies

Dr Sophie Paczesny details the incidence of graft versus host disease (GVHD) in patients receiving allogeneic transplants, and Dr Yi-Bin Chen describes the differing risk factors for acute and chronic GVHD.

Incidence and Risk Factors of Acute and Chronic GVHD

Yi-Bin Chen, MD, shares the most common GVHD prophylaxis regimens, and which regimen he typically chooses for his patients with GVHD.

Common Prophylaxis Regimens for GVHD

Drs Yi-Bin Chen and Sophie Paczesny review the diagnosis and staging of both acute and chronic GVHD, and the challenges clinicians may encounter.

Diagnosis and Stratification of Acute and Chronic GVHD

Experts discuss the current options for treating acute GVHD, including the use of corticosteroids and their management.

Frontline Treatment Options for Acute GVHD

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, detail novel strategies under investigation for the treatment of acute GVHD.

Emerging Strategies for the Treatment of Acute GVHD

Drs Paczesny and Chen explain the importance of treating chronic GVHD as early as possible, and whether steroids are still the standard first-line treatment.

The Importance of Early Treatment of Chronic GVHD

Yi-Bin Chen, MD, reviews the treatment options for patients with steroid-refractory chronic GVHD.

Treatment Options for Steroid-Refractory Chronic GVHD

Drs Yi-Bin Chen and Sophie Paczesny highlight data from key investigational approaches presented at recent meetings.

Key Investigational Approaches for Acute and Chronic GVHD

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, share their expert perspectives on how the GVHD treatment landscape is evolving.

The Evolving Field of GVHD Treatment

Insights Video Series

Frontline Treatment Options for Acute GVHD

EP: 1.Indications for Allogeneic Stem Cell Transplantation in the Treatment of Hematological Malignancies

EP: 2.Incidence and Risk Factors of Acute and Chronic GVHD

EP: 3.Common Prophylaxis Regimens for GVHD

EP: 4.Diagnosis and Stratification of Acute and Chronic GVHD

EP: 5.Frontline Treatment Options for Acute GVHD

EP: 6.Emerging Strategies for the Treatment of Acute GVHD

EP: 7.The Importance of Early Treatment of Chronic GVHD

EP: 8.Treatment Options for Steroid-Refractory Chronic GVHD

EP: 9.Key Investigational Approaches for Acute and Chronic GVHD

EP: 10.The Evolving Field of GVHD Treatment

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