Darolutamide Demonstrates Favorable Tolerability in Nonmetastatic CRPC
July 12th 2021Treatment with darolutamide induced a low cumulative incidence of hormone treatment–related adverse effects that was comparable to treatment with placebo in patients with nonmetastatic castration-resistant prostate cancer, according to findings from a safety analysis of the phase 3 ARAMIS trial.
Darolutamide Crossover Leads to High PSA Response in Nonmetastatic CRPC
Eighty-five percent of patients with nonmetastatic castration-resistant prostate cancer who crossed over from placebo to darolutamide in the phase 3 ARAMIS trial experienced a maximum prostate-specific antigen decline of at least 50% at any time of crossover.
Apalutamide Plus ADT Improves Survival Regardless of Disease Volume in mCSPC
July 12th 2021Investigators demonstrated that the benefit of androgen deprivation therapy was extended with the addition of apalutamide for patients with metastatic castration-sensitive prostate cancer regardless of disease volume.
Sequential Mitomycin/BCG Combo Shows Preliminary Safety in High-Risk NMIBC
Sequential combination treatment with mytomicin chemotherapy and Bacillus Calmette-Guérin (BCG) showed comparable safety compared with BCG alone in patients with high-risk non-muscle–invasive bladder cancer.
Urologic Care Rates Decline Across US Demographics During Height of COVID-19 Pandemic
July 9th 2021The provision of urologic care underwent a significant decline during the height of the COVID-19 pandemic across all demographic groups and practice settings in the United States, regardless of the timing of stay-at-home order mandates.