Key Updates in Lung Cancer in 2021

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Experts in lung cancer provide insight on recent data from the 2021 ASCO, ESMO, and IASLC World Conference on Lung Cancer conferences and review updates in the treatment landscape for non-small-cell lung cancer and small cell lung cancer.

EP. 1: Treatment Landscape for EGFR-Mutant Advanced NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

October 29th 2021

Ani Balmanoukian, MD, Sandip P. Patel, MD, and Heather Wakelee, MD, review currently available treatment options for EGFR-mutant advanced NSCLC and discuss their approach to frontline therapy.

EP. 2: Selecting First-line Treatment for EGFR-Mutant NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

October 29th 2021

Heather Wakelee, MD, shares insight on factors to consider when approaching the optimal first-line therapy for patients with EGFR-mutant advanced NSCLC.

EP. 3: Sequencing Treatments in EGFR-Mutant NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 5th 2021

Vamsidhar Velcheti, MD, and Stephen Liu, MD, discuss their treatment approaches for patients with EGFR-mutant NSCLC who progress on osimertinib.

EP. 4: Recent Updates in EGFR-Mutant NSCLC Treatment Landscape

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 5th 2021

Experts in lung cancer provide insight on recent updates from the ESMO Congress 2021 for the treatment of EGFR-mutant NSCLC.

$Treatment of TKI-Refractory EGFR-Mutant NSCLC$

EP. 5: Treatment of TKI-Refractory EGFR-Mutant NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 12th 2021

Heather Wakelee, MD, and Stephen Liu, MD, review the treatment of TKI-refractory EGFR-mutant NSCLC.

EP. 6: Treating EGFR Exon 20 Insertions and HER2-Mutant NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 12th 2021

Dr Vamsidhar Velcheti evaluates the use of mobocertinib in patients with EGFR exon 20 insertions, and Drs John V. Heymach and Sandip P. Patel discuss the treatment of HER2-mutant NSCLC.

EP. 7: Treatment of MET Exon 14 Mutations in NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 19th 2021

Heather Wakelee, MD, reviews key data for the treatment of MET exon 14 mutations in NSCLC as seen in the GeoMETry-III trial and the CRYSALIS study.

EP. 8: Treating ALK-Mutant and KRAS G12C–Mutant NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 19th 2021

Lung cancer experts share updates in the treatment of ALK-mutant NSCLC and KRAS G12C–mutant NSCLC as seen in the CROWN study, BrigALK2 real-world study, and CODEBreaK 100 study.

EP. 9: Treatment of Advanced NSCLC With Immune Checkpoint Inhibitors

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 24th 2021

Drs Vamsidhar Velcheti, Ani Balmanoukian, Heather Wakelee, and Stephen Liu discuss recent updates on single-agent immunotherapy regimens in patients with NSCLC.

EP. 10: Treatment of Advanced NSCLC With Dual Immune Checkpoint Inhibitors: 4-Year Update of CheckMate 227

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

November 24th 2021

Sandip P. Patel, MD, reviews updates on dual immunotherapy agents for the treatment of advanced NSCLC including the 4-year update from the CheckMate 227 study.

EP. 11: Chemoimmunotherapy in Advanced NSCLC Treatment

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 3rd 2021

Experts in lung cancer discuss recent updates from ESMO 2021 and IASLC 2021 WCLC on combination immunotherapy plus chemotherapy for the treatment of advanced NSCLC.

EP. 12: Updates From CheckMate 9LA and POSEIDON Studies in Advanced NSCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 3rd 2021

Heather Wakelee, MD, shares updates from the CheckMate 9LA study, and Vamsidhar Velcheti, MD, reviews key data from the phase 3 POSEIDON study for patients with NSCLC.

EP. 13: Role of Immunotherapy in Early Stage NSCLC Treatment

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 10th 2021

Dr Heather Wakelee reviews results from the IMpower110 study for first-line metastatic NSCLC treatment.

EP. 14: Treatment of Advanced NSCLC Following Progression on Immunotherapy

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 10th 2021

Lung cancer experts provide insight on updates from key clinical trials presented at ESMO 2021 on PD-1 inhibitor–resistant NSCLC.

EP. 15: Treatment Options for Limited-Stage SCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 17th 2021

John V. Heymach, MD, PhD, provides an overview of small cell lung cancer (SCLC), and Ani Balmanoukian, MD, reviews available treatment options for limited-stage disease.

EP. 16: IMpower133 Trial for Extensive-Stage SCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 17th 2021

Stephen Liu, MD, reviews outcomes from the IMpower133 trial and comments on the current standard of care for the first-line treatment of extensive-stage SCLC.

EP. 17: Immunotherapies in the Treatment of Extensive-Stage SCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 22nd 2021

Sandip P. Patel, MD, reviews results and clinical implications from the CASPIAN study, and Heather Wakelee, MD, shares insight on approaching the optimal immunotherapy option for patients with extensive-stage SCLC.

EP. 18: Updated Results of the CASPIAN Trial in SCLC From ESMO 2021

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 22nd 2021

John V. Heymach, MD, PhD, reviews updated results from the phase III CASPIAN trial for patients with extensive-stage SCLC (small cell lung cancer) as presented at ESMO 2021.

EP. 19: Second-Line Treatment of SCLC

By John V. Heymach, MD, PhD, MD Anderson Cancer Center
Heather Wakelee, MD, Stanford University

December 22nd 2021

Vamsidhar Velcheti, MD, leads the discussion on the current standard of care and approaching the treatment of second-line SCLC.