Targeting Mitosis: First Polo-Like Kinase Inhibitor Moves Closer to FDA Approval
September 25th 2014The concept of targeting mitotic cell division to halt the progression of rapidly dividing cancer cells has long been a staple of oncology therapy, yet chemotherapy agents that are the prime examples of this approach are nonselective in their action and can kill normal and malignant cells alike.
Changing Trends in Prostate Cancer Therapy: Is Earlier Better?
September 24th 2014Although the incidence and mortality of prostate cancer remain formidable problems in the United States, clinicians have many new agents with proven overall survival (OS) benefits to recommend for patients with metastatic disease.
Screening for Distress Now a Routine Part of Quality Cancer Care-At Last
September 23rd 2014At the 2014 ASCO meeting, OncologyLive sat down with Jimmie C. Holland, MD, the Wayne E. Chapman Chair in Psychiatric Oncology at Memorial Sloan Kettering Cancer Center and the recipient of the 2014 Giants of Cancer Careâ„¢ Award for her pioneering contributions in the field of supportive care.
Most Breast Cancer Patients Forgo Reconstruction Surgery Without Regret
September 22nd 2014Although universal insurance coverage for postmastectomy breast reconstruction has been mandated since 1998, a new study has found that the persistently high rates of American women who choose not to undergo reconstruction surgery are due primarily to patient preferences and not a lack of awareness.
Cancer Disparities Heighten Need to Recruit Hispanics for Clinical Trials
September 19th 2014The Hispanic population in the United States represents the fastest-growing segment of the population (expected to reach 30% of the nation's total by 2050), and faces significant cancer health disparities
Molecular Era Tumor Boards: Team Approach to Interpreting Genomic Test Results Proves Valuable
September 11th 2014How can a conscientious but very busy practitioner keep up with the massive quantity of molecular data that could potentially impact an individual patient with cancer? The Moores Cancer Center at the University of California, San Diego has updated the tumor board concept for the molecular era.