Brown Highlights the Rationale for the RAMP-301 Trial in Low-Grade Serous Ovarian Cancer

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Verastem Oncology, we had the pleasure of speaking with Jubilee Brown, MD, about the development of avutometinib (VS-6766) plus defactinib (VS-6063) in low-grade serous ovarian cancer. Dr Brown is a professor and director of Gynecologic Oncology at Atrium Health Levine Cancer Institute in Charlotte, North Carolina.

In our exclusive interview, Dr Brown discussed how the RAS/MAPK pathway contributes to low-grade serous ovarian cancer, unmet needs for patients with this disease, and the rationale for the ongoing phase 3 RAMP-301 trial (NCT06072781) that is evaluating avutometinib plus defactinib in this patient population.

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