Bui and Kelly Discuss the Utility of Nab-Sirolimus in Advanced Malignant PEComa

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Aadi Biosciences, we had the pleasure of speaking with Nam Bui, MD, and Ciara Kelly, MBBCh, BAO, about long-term findings from the phase 2 AMPECT trial (NCT02494570) investigating nab-sirolimus (Fyarro) in patients with advanced malignant perivascular epithelioid cell tumors (PEComa). Dr Bui is a sarcoma specialist and a clinical assistant professor of medicine at the Stanford Cancer Institute in California. Dr Kelly is the interim clinical director of the Sarcoma Oncology Service at Memorial Sloan Kettering Cancer Center in New York, New York.

In our exclusive interview, Drs Bui and Kelly discussed key long-term efficacy and safety findings from AMPECT, how nab-sirolimus performed in patients requiring dose reductions on the trial, and the clinical utility of this agent in all patients with PEComa, regardless of biomarker status.

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That’s all we have for today! Thank you for listening to this episode of OncLive On Air, sponsored by Aadi Biosciences. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

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