CRC Experts Highlight AE Management and Prevention Strategies for TAS-102/Bevacizumab, Regorafenib, and Fruquintinib

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Taiho Pharmaceutical, John H. Strickler, MD, moderated an OncLive Inside the Clinic discussion about adverse effect (AE) management for patients with colorectal cancer (CRC). Strickler is an associate professor of medicine and a member of the Duke Cancer Institute in Durham, North Carolina.

Strickler was joined by Michael Leung, PharmD, BCOP, a clinical pharmacy specialist in Gastrointestinal (GI) Medical Oncology at The University of Texas MD Anderson Cancer Center in Houston; Arvind N. Dasari, MD, MS, an associate professor in the Department of GI Medical Oncology in the Division of Cancer Medicine at MD Anderson; and Margot O’Neill, PA-C, MHS, a physician assistant in oncology at the Duke Cancer Institute.

In our exclusive interview, the panelists discussed AE monitoring and management with trifluridine/tipiracil (Lonsurf) plus bevacizumab (Avastin) for patients with previously treated, metastatic CRC; prophylactic and reactive AE management strategies when using regorafenib (Stivarga) for patients with advanced disease; and how real-world clinical experience with fruquintinib (Fruzaqla) has driven AE management for patients with metastatic disease who are receiving this agent.

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