Dr. Chi Discusses the LATITUDE Study in Metastatic Prostate Cancer

Kim Chi, MD, associate director of clinical research, Vancouver Prostate Centre, professor, Department of Medicine, University of British Columbia, discusses the LATITUDE study in metastatic prostate cancer.

This was a randomized phase III, double-blind, placebo-controlled trial that enrolled approximately 1200 men with hormone-naïve metastatic prostate cancer. Patients were randomized to receive either standard therapy with androgen-deprivation therapy (ADT) with placebo versus ADT with abiraterone acetate (Zytiga) and prednisone at 5 mg per day.

Results showed an overall survival advantage in patients who received ADT plus abiraterone acetate and prednisone, says Chi.