Dr. Epperla Discusses the Current Treatment of MCL

Narendranath Epperla, MBBS, MS, hematologist, The Ohio State University (OSU) Comprehensive Cancer Center, assistant professor in internal medicine, OSU, discusses the current treatment landscape of patients with mantle cell lymphoma (MCL).

Upfront treatment for MCL continues to be induction therapy followed by autologous stem cell transplant, says Epperla. This is based on the long term follow-up data from the NORDIC trial.

In the relapsed/refractory setting, there are many agents to choose from—BTK inhibitors, PI3-kinase inhibitors, and immunomodulatory agents. Epperla says these agents can be used in various combinations.