Video

Dr. Fraizer Discusses the MaGIC Consortium

Lindsay Frazier, MD, institute physician, Pediatric Hematology/Oncology, Dana-Farber Cancer Institute, associate professor of pediatrics, Harvard Medical School, discusses the Malignant Germ Cell International Consortium (MaGIC) in pediatric and rare tumors.

Lindsay Frazier, MD, institute physician, Pediatric Hematology/Oncology, Dana-Farber Cancer Institute, associate professor of pediatrics, Harvard Medical School, discusses the Malignant Germ Cell International Consortium (MaGIC) in pediatric and rare tumors.

MaGIC consists of the world’s leading experts in pediatric oncology, gynecologic oncology, and testicular cancer. Frazier says that all these practitioners are working together to advance the science behind germ cell tumors, and create better clinical trials for patients in these populations. The group has collected past clinical trial data in a common database to analyze and determine what questions should be addressed in future clinical trials, says Fraizer.

One of the first things that MaGIC achieved was reaching a consensus on risk of recurrence. Fraizer says that these various experts were able to have a discussion to clarify what patients are at risk for recurrence, and decide when therapy should be intensified or reduced. In the 8 years that the MaGIC Consortium has been together, they have successfully initiated 3 NCI-funded international clinical trials for patients between the ages of 0 and 50 years.

Related Videos
Alan Tan, MD, genitourinary oncology and melanoma specialist, Vanderbilt-Ingram Cancer Center; associate professor, medicine, Division of Hematology Oncology, Vanderbilt University Medical Center
Zosia Piotrowska, MD, MHS, instructor, Harvard Medical School; medical oncologist, Massachusetts General Hospital
Bartosz Chmielowski, MD
Raza Hoda, MD, FASCP
Armin Ghobadi, MD, professor, medicine, Oncology, Section of Bone Marrow Transplant; clinical director, Center for Gene and Cellular Immunotherapy, Siteman Cancer Center, Washington University
Timothy S. Fenske, MD, MS
Yair Lotan, MD, professor, urology, chief, urologic oncology, Jane and John Justin Distinguished Chair in Urology, UT Southwestern Harold C. Simmons Comprehensive Cancer Center; medical director, Urology Clinic, UT Southwestern and Parkland Health and Hospital System
Roxana S. Dronca, MD, discusses the FDA’s approval of subcutaneous nivolumab across solid tumor indications.
Craig Eckfeldt, MD
Whitney Goldsberry, MD