Video
Author(s):
Yongfeng He, PhD, discusses the identification of the GTF2I L424H mutation in mouse models of thymic cancer.
Yongfeng He, PhD, is an instructor of cancer biology in medicine at Weill Cornell Medicine in New York, New York.
He, along with Giuseppe Gianccone, MD, PhD, professor of medicine and associate director of clinical research at the Sandra and Edward Meyer Cancer Center at Weill Cornell, identified the GTF2I L424H mutation in mouse models.
Giaconne was the first to idenfiy the mutation. Together, the 2 investigators determined that this single-point mutation in thymic epithelial cells can induce thymic tumors.