Dr. Jagannath on Potential of Immunotherapy in Multiple Myeloma

Sundar Jagannath, MD, director of the Multiple Myeloma program and professor of medicine at the Tisch Cancer Institute, Mount Sinai Cancer Center, discusses the potential impact of immunotherapy in multiple myeloma.

Immunotherapy approaches may overcome mutational burdens or drug resistance in the cancer cells of this disease, says Jagannath. Monoclonal antibodies such as daratumumab (Daralex) and elotuzumab (Empliciti) are being used in newly diagnosed patients with myeloma. Additionally, checkpoint inhibitors may move upfront if they show positive results in the relapsed setting.

According to Jagannath, immuno-oncology may have a huge impact on the treatment landscape of multiple myeloma.