Video

Dr. Oxnard on the Role of Osimertinib in the TATTON Trial for Lung Cancer

Geoffrey R. Oxnard, MD, physician, assistant professor of medicine, Harvard Medical School, Dana-Farber Cancer Institute, discusses the role of osimertinib (Tagrisso) in the TATTON trial for patients with lung cancer.

Geoffrey R. Oxnard, MD, physician, assistant professor of medicine, Harvard Medical School, Dana-Farber Cancer Institute, discusses the role of osimertinib (Tagrisso) in the TATTON trial for patients with lung cancer.

The TATTON trial investigated osimertinib plus different combination therapies of durvalumab (Imfinzi), selumetinib, and savolitinib, states Oxnard.

Osimertinib with durvalumab was shown to be toxic, while osimertinib with selumetinib was found to be tolerable. Osimertinib and savolitinib is the combination that is moving forward to phase II development, explains Oxnard.

Related Videos
Alec Watson, MD
Balazs Halmos, MD
Balazs Halmos, MD
Albert Grinshpun, MD, MSc, head, Breast Oncology Service, Shaare Zedek Medical Center
Erica L. Mayer, MD, MPH, director, clinical research, Dana-Farber Cancer Institute; associate professor, medicine, Harvard Medical School
Stephanie Graff, MD, and Chandler Park, FACP
Mariya Rozenblit, MD, assistant professor, medicine (medical oncology), Yale School of Medicine
Maxwell Lloyd, MD, clinical fellow, medicine, Department of Medicine, Beth Israel Deaconess Medical Center
Neil Iyengar, MD, and Chandler Park, MD, FACP
Azka Ali, MD, medical oncologist, Cleveland Clinic Taussig Cancer Institute