Video

Dr. Secord on Treating Patients with Platinum Sensitive Ovarian Cancer

Angeles A. Secord, MD, discusses treating patients with platinum-sensitive ovarian cancer.

Video Player is loading.
Current Time 0:00
Duration 1:27
Loaded: 0%
Stream Type LIVE
Remaining Time 1:27
 
1x
  • Chapters
  • descriptions off, selected
  • captions off, selected
  • en (Main), selected

Angeles A. Secord, MD, gynecologic oncologist, Duke Cancer Center, discusses treating patients with platinum-sensitive ovarian cancer.

Often, patients with platinum-sensitive ovarian cancer do not want to restart chemotherapy, so other therapeutic options are needed, Secord says. The integration of PARP inhibitors into the treatment paradigm has called a need to evaluate patients regarding what frontline treatments they received to determine if they are eligible for a PARP inhibitor, Secord says. 

Moreover, patients are evaluated in terms of their biomarkers, including whether they harbor BRCA1/2 mutations or if their tumor is characterized by homologous recombination deficiency or proficiency, also known as genomic instability, Secord explains.

Overall, if a patient has not received a PARP inhibitor in the frontline setting and they harbor BRCA1/2 mutations or genomic instability within their tumor, they should be considered for PARP inhibitor therapy. Additionally, the use of bevacizumab (Avastin) as a therapeutic option in the maintenance setting, as well as with concurrent chemotherapy, should also be discussed with the patient, Secord concludes.

Newsletter

Stay up to date on the most recent and practice-changing oncology data