Dr. Tripathy Discusses Breast Cancer Gene Profiling

Debu Tripathy, MD, professor of medicine and co-leader of the Women’s Cancer Program at the University of Southern California Norris Comprehensive Cancer Center, discusses the primary ways that multigene profiling is used in early stage breast cancer.

Multigene gene profiling, such as the Oncotype DX score, help determine treatment in patients that are estrogen receptor (ER) positive or progesterone receptor (PR) positive and HER2 neu negative with early stage cancers. The recurrence score is used most in node negative breast cancer because the patients with an intermediate to high recurrence score are a subset of early breast cancer patients that derive the most benefit from chemotherapy.