Exploring Luspatercept's Role in Anemia Management for Lower-Risk MDS: Insights From Dr. Jorge Cortes

Welcome to OncLive On Air^®! I’m your host today, Jax DiEugenio.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by Bristol Myers Squibb, we had the pleasure of speaking with Jorge Cortes, MD, the director of the Georgia Cancer Center in Augusta, Georgia, about the integration of luspatercept-aamt (Reblozyl) into the treatment paradigm for patients with lower-risk myelodysplastic syndromes (MDS).

In our exclusive interview, Dr Cortes discussed how the FDA approval of this agent has influenced first-line MDS management, particularly for patients with anemia, and how luspatercept compares with existing treatment options like erythropoiesis-stimulating agents (ESAs). He also highlighted the quality-of-life benefits associated with luspatercept in symptomatic patients, the importance of risk stratification in lower-risk MDS, and the ultimate goals of therapy in this population. Finally, he spotlighted challenges that remain in the management of lower-risk MDS, including the need for transformative therapies that could change the natural history of the disease.

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That’s all we have for today! Thank you for listening to this episode of OncLive On Air, supported by Bristol Myers Squibb. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

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