Video

Final Comments From Panelists on Managing CML

For High-Definition, Click

In the final segment of the discussion, panelists share their closing thoughts on the treatment of patients with chronic myeloid leukemia (CML). Neil Pravin Shah, MD, stresses that monitoring patients is essential, whether they are remaining on or discontinuing therapy. In order to achieve optimal outcomes, patients with CML should be referred to a team of oncologists who are seasoned in treating this disease, particularly when a patient is not responding as well as hoped, B. Douglas Smith, MD, suggests.

There are several new therapies available for the treatment of CML, including highly active agents for patient with resistant or intolerant disease, notes Elias Jabbour, MD. These therapies enhave the importance of monitoring response. If one therapy stops working, there are other options. Most patients will do well on modern therapies, Stuart L. Goldberg, MD, adds; however, if outcomes do not seem to match expectations, seeking another interpretation of a test or finding help with a management decision could improve outcomes and result in proper care for patients.

Related Videos
Cedric Pobel, MD
Minoo Battiwalla, MD, MS
Farrukh Awan, MD, discusses treatment considerations with the use of pirtobrutinib in previously treated patients with hematologic malignancies.
Roy S. Herbst, MD, PhD, Ensign Professor of Medicine (Medical Oncology), professor, pharmacology, deputy director, Yale Cancer Center; chief, Hematology/Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; assistant dean, Translational Research, Yale School of Medicine
Haley M. Hill, PA-C, discusses the role of multidisciplinary management in NRG1-positive non–small cell lung cancer and pancreatic cancer.
Haley M. Hill, PA-C, discusses preliminary data for zenocutuzumab in NRG1 fusion–positive non–small cell lung cancer and pancreatic cancer.
Haley M. Hill, PA-C, discusses how physician assistants aid in treatment planning for NRG1-positive non–small cell lung cancer and pancreatic cancer.
Haley M. Hill, PA-C, discusses DNA vs RNA sequencing for genetic testing in non–small cell lung cancer and pancreatic cancer.
Haley M. Hill, PA-C, discusses current approaches and treatment challenges in NRG1-positive non–small cell lung cancer and pancreatic cancer.
Jessica Donington, MD, MSCR, Melina Elpi Marmarelis, MD, and Ibiayi Dagogo-Jack, MD, on the next steps for biomarker testing in NSCLC.