Opinion

Video

Intracranial Efficacy of Next-Generation ALK-Targeted Therapies

Author(s):

Balazs Halmos, MD,Julia Rotow, MD

Panelists discuss the efficacy of ALK inhibitors in treating brain metastases, referencing data from the REMARK study, the CROWN trial, ALTA-3, and ALTA-1L/brigatinib, among others.

  1. All: Please discuss the efficacy of ALK inhibitors in brain metastases.
    1. REMARK study (Xiong A, et al. 2024. WCLC. OA09.03)
    2. CROWN trial (Solomon BJ, et al. Lancet Respir Med. 2023)
    3. ALTA-3 (Yang JC, et al. J Thorac Oncol. 2023)
    4. ALTA-1L/brigatinib (Camidge DR, et al. J Clin Oncol. 2021)
  2. Others
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