Jhaveri on the INAVO120 Trial of Inavolisib/Palbociclib/Fulvestrant in PIK3CA -Mutant, HR+ Breast Cancer

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we had the pleasure of speaking with Komal Jhaveri, MD, FACP, about the phase 3 INAVO120 trial (NCT04191499), which is investigating inavolisib (GDC-0077) plus palbociclib (Ibrance) and fulvestrant (Faslodex) in patients with PIK3CA-mutant, hormone receptor–positive, HER2-negative, locally advanced or metastatic breast cancer. Dr Jhaveri is the section head of the Endocrine Therapy Research Program, the clinical director of the Early Drug Development Service, and the Patricia and James Cayne Chair for Junior Faculty at Memorial Sloan Kettering Cancer Center in New York, New York.

In our exclusive interview, Dr Jhaveri discussed key findings from the trial, the potential future implications of this research, and the importance of conducting early genomic testing to detect potential mutations in genes such as PIK3CA.

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