Commentary

Podcast

Salgia Summarizes the Benefits of Tepotinib in MET Exon 14–Mutated NSCLC

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Dr Salgia discusses how he chooses between tepotinib and capmatinib in patients with stage IV NSCLC harboring MET exon 14 skipping mutations.

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by Real Chemistry, we had the pleasure of speaking with Ravi Salgia, MD, PhD, about the use of tepotinib (Tepmetko) in patients with non–small cell lung cancer (NSCLC) harboring MET exon 14 skipping mutations. Dr Salgia is a professor and chair of the Department of Medical Oncology & Therapeutics Research, as well as the Arthur & Rosalie Kaplan Chair in Medical Oncology & Therapeutics Research at City of Hope in Duarte, California.

In our exclusive interview, Dr Salgia discussed key updated findings from the phase 2 VISION trial (NCT02864992) investigating tepotinib in patients with NSCLC with MET exon 14 skipping mutations, results from a real-world analysis comparing tepotinib vs capmatinib (Tabrecta) in patients with stage IV disease, and how he chooses between these 2 agents in the clinic.

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