Updated VISION Trial Data Showcase the Efficacy of Tepotinib in MET + NSCLC: With Martin Dietrich, MD

Welcome to OncLive On Air®! I’m your host today, Jax DiEugenio.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by Real Chemistry, we had the pleasure of speaking with Martin Dietrich, MD. Dr Dietrich is a medical oncologist at Cancer Care Centers of Brevard, The US Oncology Network, in Space Coast, Florida, as well as an assistant professor of internal medicine at the University of Central Florida College of Medicine in Orlando.

In our exclusive interview, Dr Dietrich discussed key efficacy findings from the 18-month follow-up of the phase 2 VISION trial (NCT02864992), which evaluated the efficacy of tepotinib (Tepmetko) in patients with non–small cell lung cancer harboring MET exon 14 skipping mutations. Additionally, Dr Dietrich emphasized important safety considerations with tepotinib, particularly the management of on-target adverse effects (AEs) like edema. He also discussed strategies for addressing treatment-related AEs, such as hyperalbuminemia, hyponatremia, and kidney function abnormalities, and highlighted the importance of careful monitoring to make dose adjustments as necessary.

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That’s all we have for today! Thank you for listening to this episode of OncLive On Air, supported by Real Chemistry. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

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