Management of Hepatocellular Carcinoma: Future Directions in Care
Expert insight to how the field of hepatocellular carcinoma management may evolve in coming years given therapeutic combinations and ongoing clinical trials.
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Patient Profile 3: Advanced HCC Treated With Cabozantinib in Second Line
Centering discussion on the final patient profile, panelists consider how they select optimal therapy in the second-line setting of advanced hepatocellular carcinoma.
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Treatment Options for Advanced HCC in the Second-Line and Beyond
Brief but comprehensive insight to the cornerstone second-line treatment options in the setting of recurrent advanced hepatocellular carcinoma.
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Novel First-Line Immunotherapy Approaches in Advanced HCC
Panelists close out their discussion on first-line treatment options for advanced HCC with a review of single-agent and combination immunotherapy approaches.
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Real-World Use of Durvalumab + Tremelimumab in Advanced HCC
In the context of clinical data from the HIMALAYA and STRIDE trials, expert oncologists review real-world use of tremelimumab + durvalumab in advanced HCC.
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Patient Profile 2: A 70-Year-Old Man With Advanced HCC Treated With Durvalumab + Tremelimumab
Focusing on a second patient profile of advanced hepatocellular carcinoma, panelists consider the role of first-line tremelimumab + durvalumab.
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Real-World Use of First-Line Lenvatinib Therapy in Advanced HCC
Comprehensive discussion on the real-world applications of first-line lenvatinib therapy in advanced HCC followed by its potential in combination with TACE.
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Advanced HCC: Clinical Trial Data Behind First-Line Therapy Options
Expert oncologists take a look at clinical trial data as they pertain to prevalent first-line systemic therapy options in advanced hepatocellular carcinoma.
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Selecting the Appropriate First-Line Therapy for Advanced HCC
In the context of the first patient profile, expert panelists consider which factors play into their selection of first-line systemic agents in advanced hepatocellular carcinoma.
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Patient Profile 1: A 77-Year-Old Man with Advanced HCC Treated With Lenvatinib
Focusing on the first patient profile of advanced hepatocellular carcinoma, Andrea Casadei-Gardini, MD, reviews his selection and use of first-line lenvatinib therapy.
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Advanced HCC: Updates in First-line Systemic Therapy
Moderator Josep Llovet, MD, centers discussion on advanced hepatocellular carcinoma and provides a broad overview of treatment options in the frontline setting.
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Role of Systemic Therapy in Early- or Intermediate-Stage HCC
Expert perspectives on the selection and use of systemic therapy in patients who progress on or are unsuitable for locoregional therapies.
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Role of Locoregional Therapy in Early- or Intermediate-Stage HCC
Comprehensive insight on the role of locoregional therapies in early- or intermediate-stage HCC, alone or in combination with systemic agents.
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Early- and Intermediate-Stage HCC Treatment Landscape
Opening their discussion on the management of hepatocellular carcinoma, expert panelists take a broad look at the treatment landscape.
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Future Directions for HCC Management
Drs Josep Llovet, Stephen L. Chan, and Andrea Casadei Gardini discuss the future treatment landscape for HCC.
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Management of Advanced HCC Associated With NASH
Stephen L. Chan, MD, leads the discussion on the prevalence and management of advanced HCC in patients with NASH.
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Treatment Options for Advanced HCC With Underlying NASH
A panel of experts in gastroenterology review the case of a 65-year-old man with advanced HCC associated with NASH and comment on treatment with TKIs and immunotherapy.
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Sequencing Systemic Therapy for Advanced HCC
Andrea Casadei Gardini, MD, leads the discussion on the optimal sequencing of systemic therapy for advanced HCC.
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Optimizing the Selection of Frontline TKIs for Advanced HCC
Experts in gastroenterology share their approaches to first-line single-agent and combination TKI therapies for the treatment of advanced HCC.
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Updates to First-line Treatment Options for Advanced HCC
Andrea Casadei Gardini, MD, presents the case of a 63-year-old man diagnosed with advanced HCC, and the panel reviews available first-line treatment options for patients with advanced HCC.
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Is There a Role for Systemic Therapy for Patients With Intermediate HCC?
Gastroenterology experts discuss whether there a is a role for systemic therapy for the management of intermediate HCC.
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Role of TACE and TARE in the Treatment of HCC
Andrea Casadei Gardini, MD, and Stephen L. Chan, MD, examine the use of TACE and TARE-Y90 for the treatment of HCC.
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Updates to Adjuvant and Neoadjuvant Therapy in Early HCC
Stephen L. Chan, MD, reviews the case of a 72-year-old woman with mild alcoholic cirrhosis and provides insight on the potential role of adjuvant and neoadjuvant therapy for the treatment of HCC.
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