Higher Dose of Ipilimumab Added to Nivolumab Effective in Bladder Cancer
October 22nd 2018Extended follow-up data from the CheckMate-032 study shows a trend toward higher overall response and longer progression-free survival with the regimen of nivolumab at 1 mg/kg plus ipilimumab at 3 mg/kg in patients with platinum-pretreated metastatic urothelial carcinoma.
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Olaparib Substantially Improves PFS as Frontline Maintenance in Ovarian Cancer
October 22nd 2018The PARP inhibitor olaparib significantly improved progression-free survival as frontline maintenance therapy for women with BRCA-positive advanced ovarian cancer, according to findings from the randomized phase III SOLO-1 trial.
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Tepotinib Plus Gefitinib Improves PFS in MET+ EGFR-Mutant NSCLC
October 21st 2018The combination of tepotinib plus gefitinib improved progression-free survival and overall response versus chemotherapy in patients with MET mutated EGFR-positive non–small cell lung cancer resistant to prior EGFR TKI therapy.
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Gomella Gives Update on Nonmetastatic CRPC Advances
October 19th 2018Leonard G. Gomella, MD, professor, chair, Department of Urology, director, Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital, discusses the shifting landscape of nonmetastastic CRPC, along with other developments across the prostate cancer paradigm.
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Molecular Testing, Immunotherapy To Be Highlighted at 20th Annual Breast Cancer Conference
September 29th 2018Advances in subtype-specific treatments, immunotherapy, ongoing issues with younger patients, the optimal use of neoadjuvant and adjuvant regimens, and molecular testing will be discussed at the 20th Annual Lynn Sage Breast Cancer Symposium.
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