Antibody-Drug Conjugate Under Study in Platinum-Resistant Ovarian Cancer
February 28th 2017A novel targeted therapy, mirvetuximab soravtansine (IMGN853), is being investigated as a single-agent treatment for patients with advanced, platinum-resistant epithelial ovarian cancer with medium and high expression levels of folate receptor-alpha in an effort to provide an effective option for a population facing a difficult prognosis.
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First SITC Guidelines in RCC Address Continuing Role of Interleukin-2 and Emergence of Nivolumab
February 21st 2017New guidelines involving the immunotherapies nivolumab (Opdivo) and interleukin-2 inhibitors have been issued by The Society for Immunotherapy of Cancer to help practicing clinicians manage patients with renal cell carcinoma.
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Veliparib Facing Phase III Test in BRCA-Positive Breast Cancer
January 12th 2017Researchers are seeking to determine whether adding the PARP inhibitor veliparib to a chemotherapy combination will improve outcomes for patients with HER2-negative, germline BRCA-associated metastatic or locally advanced breast cancer.
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Novel Interleukin-Based Immunotherapy Under Study in Pancreatic Cancer
December 29th 2016An immunotherapy combination that adds the interleukin-10 agonist AM0010 to FOLFOX chemotherapy will be evaluated in a phase III trial for patients with metastatic pancreatic cancer that could introduce a new modality to the treatment paradigm for the malignancy.
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Sanofi's Halt of BCG Production Worries Bladder Cancer Patients and Urologists
December 1st 2016Sanofi Pasteur plans to discontinue production of Bacillus Calmette-Guérin for the US market by mid-2017, startling physicians and patients who fear that a shortage of the widely used bladder cancer therapy will develop.
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