Ibrutinib Benefit in Waldenstrom Macroglobulinemia Sustained With Latest Data
March 2nd 2017Single-agent ibrutinib induced a response rate of 90% at a median follow-up of 18.1 months in rituximab-refractory patients with Waldenstrom macroglobulinemia, according to results from an open-label substudy of the ongoing phase III iNNOVATE trial published in The Lancet Oncology.
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Biomarkers Show Efficacy of Radium-223/Docetaxel Combo in mCRPC
February 28th 2017Michael J. Morris, MD, discusses a phase I/II trial in which the combination of radium-223 (Xofigo) and docetaxel had a greater effect than docetaxel alone on bone biomarkers in patients with bone-metastatic castration-resistant prostate cancer.
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Intermittent Sunitinib Feasible in Metastatic Renal Cell Carcinoma
February 9th 2017The findings from the phase II study of intermittent sunitinib in patients with previously untreated metastatic renal cell carcinoma demonstrate that periodic extended sunitinib treatment breaks are feasible and the clinical efficacy does not seem to be compromised.
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