Clinical Scenario: A 74-Year-Old with Cytopenic Myelofibrosis
Rami Komrokji, MD, presents to the panel a second clinical scenario of a 74-year-old with cytopenic myelofibrosis.
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Myelofibrosis Treatment Approaches after Disease Progression
A look at the potential treatment options for a patient with myelofibrosis who progresses after first-line therapy.
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Clinical Scenario: A 67-Year-Old with Myelofibrosis
Key opinion leaders discuss how they would approach treating a 67-year-old with myelofibrosis, presenting with splenomegaly.
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Management of Accelerated Phase Myeloproliferative Neoplasms
Drs Palmer and Mesa explain the challenges of treating accelerated phase myeloproliferative neoplasms.
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Momelotinib in Myelofibrosis Treatment: Updates from ASCO 2022
Ruben Mesa, MD, discusses updates on the novel agent momelotinib from an abstract he presented at ASCO 2022.
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Efficacy and Safety of JAK Inhibitors for Myelofibrosis
Jamile Shammo, MD, FACP, explains the efficacy and safety of the 3 approved therapies for myelofibrosis.
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Risk Stratification for Myelofibrosis
The panel has a conversation on risk stratification for myelofibrosis and how it individualizes their treatment approaches.
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Myeloproliferative Neoplasms: Myelofibrosis
Dr Jamile Shammo explains the process of diagnosing myelofibrosis and highlights the importance of bone marrow biopsies.
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Assessing Symptom Burden and Quality-of-Life for Myeloproliferative Neoplasms
A discussion on assessing symptom burden and quality of life for patients with essential thrombocythemia or polycythemia vera.
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PTG-300 Therapy for Phlebotomy-Dependent Polycythemia Vera
Ruben Mesa, MD, details an abstract presented at ASCO 2022 on an investigational agent filling an unmet need in polycythemia vera.
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Myeloproliferative Neoplasms: Polycythemia Vera
Jamile Shammo, MD, FACP, FASCP, defines polycythemia vera and explains the process for diagnosis and risk stratification.
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Managing Patients with Essential Thrombocythemia
Dr Ruben Mesa describes how he treats patients with essential thrombocythemia and the available treatment options.
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Promising Data for Pevonedistat in High-Risk MDS
Amy DeZern, MD, MHS leads a discussion surrounding the mechanism of action and clinical trial data on the use of magrolimab and pevonedistat in patients with high-risk myelodysplastic syndrome.
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Emerging Role of Venetoclax in the Treatment of MDS
Rami Komrokji, MD and Gail Roboz, MD, discuss treatment considerations and clinical trial data surrounding the use of venetoclax in patients with myelodysplastic syndrome or acute myeloid leukemia.
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Treatment in Older Patients with High-Risk MDS
Azra Raza, MD, discusses considerations for use of hypomethylating agents in older patients with high-risk myelodysplastic syndrome.
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The panel of experts comment on the optimal timing of hypomethylating agents and transplant in patients with high-risk myelodysplastic syndrome.
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Use of HMAs for the Treatment of MDS
The panel of experts highlight the risk factors and considerations for use of hypomethylating agents in patients with myelodysplastic syndrome versus acute myeloid leukemia.
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Treatment of Transfusion Dependent MDS
The panel of experts reflect on the use of lenalidomide in patients with myelodysplastic syndrome who are transfusion dependent.
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Luspatercept: An Erythroid Maturation Agent in MDS
Rami Komrokji, MD discusses the recent approval and FDA indication for the use of the erythroid maturation agent luspatercept.
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ESA Use in the Treatment of MDS
The panel of experts discusses considerations necessary when recommending treatment with erythropoiesis-stimulating agents in patients with myelodysplastic syndrome.
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Guidelines for the Treatment of MDS
Rami Komrokji, MD, discusses his approach to treatment in patients with myelodysplastic syndrome, while being mindful of recommended guidelines.
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Individualized Treatment for MDS
The panel of leukemia experts highlight the importance of individualized treatments for patients with myelodysplastic syndrome.
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Staging Models in Diagnosis and Risk Assessment of MDS
Rami Komrokji, MD, and Gail Roboz, MD, discuss the importance of staging models in the diagnosis and routine assessment of patients with myelodysplastic syndrome.
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