Targeted Therapies Improve Outcomes in Advanced Thyroid Cancer
November 5th 2015The kinase inhibitors sorafenib and lenvatinib have significantly altered the treatment paradigm for patients with advanced radioactive iodine-refractory differentiated thyroid cancer in both older and younger populations.
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Early Marketing of ROCA CA-125 Ovarian Test Sparks Concern
October 7th 2015The jury is still out on whether use of an algorithm to help classify risk levels in ovarian cancer can improve overall survival but a company is already marketing the system in Britain and plans to bring it to the United States before the end of the year.
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Drug Shortages Persist Despite FDA Push for More Information
October 1st 2015The door isn't fully closed on the acute oncology drug shortages of 4 years ago, observers say, though the FDA has established rules for greater disclosure by manufacturers and continues to tweak guidelines that would require far more information about manufacturing processes and production issues.
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Daraprim Underscores Need for Drug Pricing Reform
September 24th 2015The attempt by Turing Pharmaceuticals to boost the price of the anti-parasitic pyrimethamine (Daraprim) 5500% is now under reconsideration, owing to a firestorm of public and institutional protest, but it doesn't solve the problem of no limits on what manufacturers can charge and the lack of drug pricing transparency.
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ABIM Poised to Scrap 10-Year MOC Requirements
September 17th 2015The American Board of Internal Medicine says it is working to incorporate a set of changes to its physician Certification and Maintenance of Certification requirements that physicians have complained are out of step with the realities of their work.
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Alternative Payment Plan Works Only With Large Patient Cohorts
September 11th 2015The experiment with bundled care in oncology is moving forward despite mixed results and lingering concerns about the administrative difficulty of implementation, potential care compromises, and whether innovation can thrive under fixed payments.
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Necitumumab Assigned "Low Value" in Lung Cancer by Emory and Georgia Tech
August 28th 2015New drug candidate necitumumab, which is being reviewed by the FDA as a treatment for patients with locally advanced or metastatic squamous non-small cell lung cancer, received a low cost-effectiveness evaluation in a study published in JAMA Oncology.
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Checkpoint Inhibitors Show Promise in Triple-Negative Breast Cancer
August 28th 2015Immune checkpoint inhibitors can be of significant value in combatting recurrent and metastatic triple negative breast cancer, Rita Nanda, MD, told physicians at the recent 14th Annual International Congress on the Future of Breast Cancer.
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NCCN Strives to Control Cost of Cancer Drugs With New Evaluation Framework
August 25th 2015As cancer drugs soar in price, the National Comprehensive Cancer Network is introducing cost as a measure of the overall value of a therapy, following the trail of ASCO and a doctor from Memorial Sloan Kettering Cancer Center in attempting to put a lid on drug inflation.
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Oncologists Urged to Help Obese Breast Cancer Patients Manage Weight
August 12th 2015There is clear evidence that obesity at the time of diagnosis of operable breast cancer is associated with an increased risk of distant recurrence, specifically for HR–positive, HER2-negative disease, and oncologists should consider helping patients better manage their weight as part of their treatment plans.
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Soaring Prices for Oncolytics Prompt Payer Pushback
June 26th 2015With the cost of newer immunotherapy drugs soaring into the tens of thousands of dollars per month, payers are under increasing pressure to control spending and are tightening the spigot in various ways, oncology professionals told OncLive in a series of interviews.
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Doctors Wary of Social Media Exposure But See Value in Dialogue
June 12th 2015Social media – which broadly defined encompasses many different forms of Web-based exchange – has the potential to make a deep imprint on oncology practice, but many clinicians are still reluctant to participate.
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ASCO Offers Data Sharing to Help With Value Transition
May 28th 2015PracticeNET is an initiative emerging from ASCO's Clinical Affairs Department designed to help practices learn from one another's successes as they move farther away from fee-for-service and toward increasingly cost-effective models of care.
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Drug Revenues May Migrate to Specialty Pharma
May 14th 2015The rising number of oral oncology drugs that can be supplied through pharmacy networks rather than administered in clinical settings, such as intravenous drugs, has many physicians worried that they are losing control of an important part of the therapeutic process.
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