VICTORIA (NCT05192642), is an exact-matching study comparing the outcomes of patients with TRK fusion cancer treated with larotrectinib in 3 clinical trials (NCT02122913, NCT02576431, NCT02637687) to patients treated with non-TRK inhibitor therapies in the real-world (RW) setting.
Read More
Investigational Agents in SCLC in the Second Line Setting and Beyond
Taofeek Owonikoko, MD, PhD, highlights investigational agents and ongoing clinical trials in SCLC he looks forward to.
Read More
Choosing the Appropriate Treatment in the Second Line Setting in SCLC
Experts provide insights on choosing the optimal therapy in patients with small cell lung cancer in the second line and beyond.
Read More
Patient Profile 3: A 70-Year-Old Man with SCLC Receiving Chemotherapy in the Second-Line Setting
Dr Jared Weiss presents the profile of a 70-year-old male patient with SCLC who received chemotherapy in the second line setting for discussion to the panel.
Read More
Lurbinectedin for SCLC Treatment in the Second-Line Setting
Dr Vivek Subbiah explains the clinical trial data that led to the approval of lurbinectedin for SCLC treatment.
Read More
Second Line Treatment Options in SCLC and Selecting the Appropriate Therapy
The panel discusses the second line treatment options in SCLC and how they choose among the various options based on patient and disease characteristics.
Read More
Patient Profile 2: A 60-Year-Old Man with SCLC Progressing on First-Line Therapy
Vivek Subbiah, MD, MPH, presents the patient profile of a 60-year-old man with SCLC who progressed on frontline therapy.
Read More
Ongoing Trials and Real-World Studies in Frontline SCLC
Dr Charles Rudin highlights other notable clinical trials and real-world studies in patients with SCLC in the frontline setting.
Read More
IMpower 133 Trial and Patient Selection for Durvalumab + Chemotherapy vs Atezolizumab + Chemotherapy
Dr Charu Aggarwal shares data from the IMpower133 trial of atezolizumab plus chemotherapy for SCLC, and how to select the appropriate frontline therapy.
Read More
Management of Adverse Events Associated with Durvalumab + Chemotherapy
Vivek Subbiah, MD, analyzes adverse events observed with durvalumab plus chemotherapy in patients with SCLC and how they can be managed.
Read More
Frontline Therapy for SCLC: The CASPIAN Trial of Durvalumab + Chemotherapy
Jared Weiss, MD, reviews data from the CASPIAN trial of durvalumab plus chemotherapy in patients with extensive-stage small cell lung cancer.
Read More
Patient Profile 1: A 68-Year-Old Male with SCLC and Brain Metastases
Charu Aggarwal, MD, MPH, presents the profile of a patient with small cell lung cancer with brain metastases to spark a discussion on treatment approaches in the frontline setting.
Read More
Overview of SCLC and Importance of Early Diagnosis
Drs Owonikoko and Weiss provide a brief overview of small cell lung cancer and the vital importance of an early diagnosis to improve patient outcomes.
Read More