Authors
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Donna Shalala on New Healthcare ReformDonna Shalala, PhD, President, University of Miami, discusses the new healthcare reform in the U.S.
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Dr. Germain on Scientific Rationale Behind Bortezomib/Fulvestrant for HR+ Breast CancerDoris Germain, PhD, ‎associate professor at Mount Sinai Cancer Institute, discusses the scientific rationale behind a clinical trial comparing fulvestrant alone with bortezomib plus fulvestrant for the treatment of hormone receptor-positive metastatic breast cancer.
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Short Course Radiation Treatment for Breast CancerActive research and advancements in the field focuses on lessening the burden of radiation treatment while still maintaining acceptable cosmetic outcomes for patients with breast cancer.
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Dr. Keefe on the Role of Supportive Care in Personalized MedicineDorothy M. K. Keefe, MD, FRACP, past president, MASCC, director, SA Cancer Service, professor of cancer medicine, University of Adelaide, Australia, discusses the role of supportive care in personalized medicine.
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Dr. Kondziolka on Therapy for Patients With Melanoma Who Have Brain MetsDoug Kondziolka, MD, professor and vice chair of Clinical Research, NYU Langone Medical Center, discusses therapeutic approaches for patients with melanoma who have brain metastases.
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Unlocked Genomes Provide Clinical Answers, But Questions About Universal Test Catalog RemainAlthough we've known for decades that heredity is a major factor in cancer susceptibility and management, the insights gained in the past decade are still breathtaking.
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Dr. Levine Discusses a Combination Study in Endometrial CancerDouglas A. Levine, MD, professor, Department of Obstetrics and Gynecology, director, Division of Gynecologic Oncology, NYU Langone's Perlmutter Cancer Center, discusses the randomized NRG Oncology Group 86P study for patients with endometrial cancer.
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Dr. Nelson on the Future Utility of ctDNA in CRCDouglas A. Nelson, MD, discusses the future utility of circulating tumor DNA in colorectal cancer.
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Parotid Node Metastases in Locally Advanced Nasopharyngeal and Oropharyngeal Cancer: Implications for Radiotherapy Target Volume DelineationThe ipsilateral parotidean nodes may be at risk of metastatic involvement when bulky ipsilateral level II metastases and multilevel nodal disease are co-existent, possibly due to retrograde lymphatic drainage.
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Dr. Douglas Evans on Neadjuvant Therapy for Pancreas CancerDouglas B. Evans, MD, FACS, Chair, Professor, Donald C. Ausman Family Foundation Professor of Surgery, Medical College of Wisconsin, discusses how to appropriately sequence therapies for pancreatic cancer.
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Dr. Johnson on the Rationale for Examining Chronic irAEs Associated With Anti-PD-1 Therapy in MelanomaDouglas B. Johnson, MD, discusses the rationale for examining chronic immune-related adverse effects associated with anti–PD-1 therapy in patients with high-risk resected melanoma.
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Dr. Marks on Investigational Antibody-Drug Conjugates in HER2+ Breast CancerDouglas K. Marks, MD, discusses investigational antibody–drug conjugates in HER2-positive breast cancer.
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Dr. Kondziolka Discusses Updates in the Treatment of Brain MetastasesDouglas Kondziolka, MD, MSc, director, Gamma Knife Program, vice chair, Clinical Research, Departments of Neurosurgery and Radiation Oncology, Perlmutter Cancer Center at NYU Langone, discusses updates concerning the treatment of brain metastases.
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Phase II Clinical Trial of Intratumoral Dendritic Cells Injections and Neoadjuvant Radiotherapy in Resectable Soft Tissue SarcomasNeoadjuvant radiation with dendritic cell injections has the potential to be safe, effective, and immunogenic in high-grade soft tissue sarcoma and needs to be confirmed in randomized larger clinical trials.
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Z-Code Identifiers Give Providers Objective Information About Molecular TestsVirtually everyone in the clinical laboratory business is now acquainted with Z-code identifiers. Each unique laboratory test should have a unique tracking code, even if more than one Z-code identifier is reported with a corresponding American Medical Association's Current Procedural Terminology (CPT) billing code.
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Dr. Doug Lowy on Preventing Cancer Through VaccinationDouglas R. Lowy, MD, acting director, National Cancer Institute, chief, Laboratory of Cellular Oncology, senior Investigator, Head, Signaling and Oncogenesis Section, discusses vaccines that may show efficacy in certain tumor types.
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Dr Yee on Neoadjuvant Datopotamab Deruxtecan Plus Durvalumab in Early-Stage Breast CancerDouglas Yee, MD, discusses datopotamab deruxtecan and durvalumab in the neoadjuvant setting for early-stage breast cancer.
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Dr. Adam Bass on the Origins of Different Gastric Tumor TypesDr. Adam Bass, MD, Dana-Farber Cancer Institute, discusses the causes for different types of gastric cancer.
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Dr. George Somlo on Advances in Multiple MyelomaDr. George Somlo, MD, medical oncologist, City of Hope, discusses recent highlights in multiple myeloma.
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Dr. Hisham Mehanna on Quality of Life Differences in Head and Neck Squamous Cell CancerHisham Mehanna, MBChB, PhD, Chair, Head and Neck Surgery, Director, Institute of Head and Neck Studies and Education at University of Birmingham, discusses differences in the quality of life (QoL) and functional outcomes of treatment between HPV-positive and HPV-negative head and neck squamous cell cancer patients (HNSCC).
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Dr. Jordi Bruix on the Impact Regorafenib Will Have on Liver Cancer TreatmentDr. Jordi Bruix, MD, head of the Barcelona Clinic Liver Cancer (BCLC) at University of Barcelona, discusses the major impact that regorafenib (Stivarga) will have for the treatment of hepatocellular carcinoma (HCC).
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Dr. Navesh K. Sharma on Older Patients Tolerating Internal RadiationDr. Navesh K. Sharma, associate professor of Radiology in the Division of Radiology and Oncology at Penn State Hershey Medical Center and section chief of Radiation Oncology at the Penn State Health St. Joseph Cancer Center, discusses that age should not be a deciding factor in giving internal radiation to patients with liver cancer.
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BiTE Platform and the Evolution Toward Off-The-Shelf Immuno-Oncology ApproachesAmgen Oncology is committed to investigating innovative approaches to fighting cancer, across both hematological malignancies and solid tumors.
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Dr. Volker Heinemann on the Addition of SIRT to Chemotherapy for mCRCVolker Heinemann, MD, PhD, director of the Comprehensive Cancer Center at Ludwig Maximilian University of Munich, discusses how depth of response, which is highly correlated with overall survival, was improved for patients with metastatic colorectal cancer who added selective internal radiation therapy (SIRT) to chemotherapy.
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Dr. Yael Cohen on Anti-Angiogenic Agent VB-111Yael Cohen, MD, vice president of Clinical Development at VBL Therapeutics Pharmaceuticals, discusses VB-111, a highly targeted anti-angiogenic agent that is being investigated in several tumor types.
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Dr. Moghanaki on Remaining Questions Following the CheckMate-816 Trial in NSCLCDrew Moghanaki, MD, MPH, discusses questions that still need to be addressed following the phase 3 CheckMate-816 trial of the neoadjuvant combination nivolumab plus chemotherapy in patients with non–small cell lung cancer.
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Dr. Dung Le on Biomarker for PD-1 Agents in CRCDung T. Lee, MD, assistant professor of Oncology, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, discusses a biomarker for PD-1 agents in colorectal cancer (CRC).
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Phase II Clinical Trial of Intratumoral Dendritic Cells Injections and Neoadjuvant Radiotherapy in Resectable Soft Tissue SarcomasNeoadjuvant radiation with dendritic cell injections has the potential to be safe, effective, and immunogenic in high-grade soft tissue sarcoma and needs to be confirmed in randomized larger clinical trials.
Latest:
Precision Medicine Modeling Helps Advance Colorectal Cancer CarePreclinical mouse models and cell lines link colorectal cancer subtypes subtypes with potential therapies.
