The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
ASCO Supports ACS Guidelines for Prostate Cancer Survivor Care
February 15th 2015ASCO has endorsed new prostate cancer survivorship care guidelines from the American Cancer Society that provide a structure to help prostate cancer specialists and primary care physicians deliver high quality of care to patients with localized disease.
First Oral Proteasome Inhibitor Meets PFS Endpoint in Phase III Myeloma Trial
February 11th 2015The proteasome inhibitor ixazomib met its primary endpoint of improving progression-free survival at a prespecified interim analysis of a phase III trial of patients with relapsed/refractory multiple myeloma.
Sherman Says Lenvatinib Approval "Likely" as FDA Decision Date Nears
February 11th 2015With a deadline of April 14, the FDA will soon make its final approval decision on the oral multikinase inhibitor lenvatinib as a treatment for patients with progressive, radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC).
Rutgers Cancer Institute of New Jersey Joins OncLive Strategic Alliance Partnership Program
February 10th 2015OncLive today welcomes Rutgers Cancer Institute of New Jersey as a partner in promoting awareness of the most recent advances in cancer care through OncLive's Strategic Alliance Partnership program
Fox Chase Cancer Center Joins Onclive® in Strategic Alliance Partnership Program
February 3rd 2015OncLive® and Fox Chase Cancer Center, a National Cancer Institute (NCI)-designated Comprehensive Cancer Center that is part of the Temple University Health System in Philadelphia, announced that they have joined forces to raise awareness of significant oncology research and clinical practice news through OncLive's Strategic Alliance Partnership program.
FDA Grants Breakthrough Status to PD-L1 Inhibitor MPDL3280A in NSCLC
February 2nd 2015The anti–PD-L1 agent MPDL3280A has received a breakthrough therapy designation from the FDA for PD-L1–positive non–small cell lung cancer that has progressed during or after platinum-based chemotherapy, as well as a targeted therapy for patients with EGFR- or ALK-positive tumors.
Yale Scientist Wins International Award for Discoveries Leading to New Class of Cancer Drugs
February 2nd 2015A Spanish foundation has awarded a major scientific prize to Yale researcher Joseph Schlessinger and two colleagues in recognition of their work leading to the first personalized treatments for cancer. The 2015 Frontiers of Knowledge Award in Biomedicine from the Madrid-based BBVA Foundation includes a €400,000 cash priz
President Details $215 Million 'Precision Medicine Initiative'
January 31st 2015The 'precision medicine initiative' proposed by President Barack Obama will require an initial investment of $215 million and consent from 1 million volunteers, with the goal of discovering potential cures for patients with cancer.
More Positive Data for BRAF/MEK Combo in Melanoma, But Debate Continues
January 29th 2015The combination of trametinib (Mekinist) and dabrafenib (Tafinlar) improved overall survival (OS) compared with vemurafenib alone in patients with unresectable (stage IIIC) or metastatic (stage IV) BRAFV600E/K mutation-positive cutaneous melanoma.