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Academic Perspectives for the Management of HPV-Positive HNSCC

Panelists discuss how human papillomavirus (HPV)–related tumors vary in aggressiveness, with HPV-positive head and neck squamous cell carcinoma (HNSCC) presenting unique challenges. Key treatment hurdles include tumor heterogeneity, resistance development, and optimizing de-escalation strategies while maintaining efficacy.

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Video content above is prompted by the following:

  • Are certain types of HPV-related tumors more difficult to treat or more aggressive than others?
  • What are the primary challenges clinicians face when treating HPV-positive HNSCC?

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