Opinion

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Biomarker Testing Best Practices in HR+/HER2- mBC

Adam M. Brufsky, MD, PhD, and Erika P. Hamilton, MD, delve into the most clinically significant genomic tests and biomarker assays employed in HR+/HER2- breast cancer, focusing on BRCA mutations, PI3 alterations, AKT alterations, and PTEN alterations, which play crucial roles in determining prognosis and guiding treatment decisions.

  1. Please discuss the role of biomarker testing in HR+/HER2- breast cancer.
    • What are the most clinically relevant genomic tests or biomarker assays used in HR+/HER2- breast cancer?
    • How do the results of these tests influence prognosis and treatment decision-making?
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