Curigliano on the DESTINY-Breast06 Trial in HER2-Low and -Ultralow Metastatic Breast Cancer

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Daiichi Sankyo, we had the pleasure of speaking with Giuseppe Curigliano, MD, PhD, about the phase 3 DESTINY-Breast06 trial (NCT04494425) investigating fam-trastuzumab-deruxtecan-nxki (Enhertu) in patients with HER2-low or HER2-ultralow metastatic breast cancer. Dr Curigliano is the director of the Early Drug Development Division and co-chair of the Experimental Therapeutics Program at the European Institute of Oncology in Milan, Italy.

In our exclusive interview, Dr Curigliano discussed the unique characteristics of the DESTINY-Breast06 patient population, key efficacy findings from the trial, and the importance of expanding pathology assessments to include all established subgroups of HER2 expression.

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