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J. Bradley Elder, MD, discusses blinded early-safety data from a phase 2b trial of IGV-001 in patients with newly diagnosed glioblastoma.

Dr Elder on the Initial Safety Profile of IGV-001 in Newly Diagnosed Glioblastoma

Rimas V. Lukas, MD, discusses the efficacy of eflornithine plus lomustine in recurrent IDH-mutant anaplastic astrocytoma per 2021 WHO diagnostic criteria.

Dr Lukas on Survival Outcomes With Eflornithine in IDH-Mutant Anaplastic Astrocytoma 

IGV-001, an autologous cell immunotherapy, demonstrated an acceptable safety profile in patients with newly diagnosed glioblastoma.

IGV-001 Showcases Positive Benefit-Risk Profile in Newly Diagnosed Glioblastoma

Paolo Caimi, MD, discusses the rationale behind evaluating LMY-920, a novel BAFF CAR T-cell therapy, in relapsed/refractory non-Hodgkin lymphoma.

Dr Caimi on Early Data for LMY-920 in R/R B-Cell NHL

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Jairam Krishnamurthy, MD, FACP, details what to take into consideration when implementing 2024 Breast Cancer NCCN guideline changes into everyday practice. 

Category 1 Recommendation of Ribociclib Plus an AI Represents Huge Advancement in Breast Cancer

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Francisco J. Esteva, MD, PhD, highlights various pivotal studies for the treatment of HER2-positive early-stage breast cancer.

Long-Term Findings Solidify Role of HER2-Targeted Therapy in Early HER2+ Breast Cancer

Lu Chen, PhD, an Assistant Professor in the Nuclear Dynamics and Cancer Research Program has received a grant from the NIH to further investigate the role of RNA and the formation of liquid droplet structures within cancer cells.

Fox Chase Cancer Center Researcher Lu Chen Receives $250,000 NIH Grant to Further Investigation of RNA

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Optimizing Therapy for Patients with Acute and Chronic Graft-Versus-Host Disease (GvHD)

OncLive Peer Exchange® 

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Moderator Michael Bishop, MD leads a discussion with panelists Hannah Choe, MD, Doris M. Ponce, MD, and Bart L Scott, MD, concerning recent updates in the prevention, diagnosis, and treatment of Graft-Versus-Host Disease.

Moderator Michael Bishop, MD introduces expert panelists and leads an overview of Graft-Versus-Host Disease, covering the differences between chronic and acute conditions, how GvHD is typically diagnosed, and GvHD risk assessment. 

Understanding Chronic and Acute Graft-Versus-Host Disease Presentation and Diagnosis

Panelists Hannah Choe, MD, and Bart L Scott, MD share insights concerning prophylaxis in Graft-Versus-Host Disease, including key study data and current standards of care as well as discuss the potential role of biomarkers in GvHD. 

Improving Patient Outcomes: Prophylactic Options in Graft-Versus-Host Disease

Subject-matter experts delve into the diagnosis, risk assessment, and treatment selection process for acute GvHD, emphasizing differentiation of refractory disease.

Optimal First-Line Treatment Approaches for Acute GvHD

Treatment options for steroid refractory acute GvHD, including ruxolitinib efficacy and NCCN guideline adherence, take center stage in the discussion.

Treatment Options in Steroid-Refractory Acute GvHD

Supportive care measures for acute GvHD are explored, highlighting strategies to manage symptoms and improve patient well-being.

Enhancing Patient Care in Acute GvHD: Supportive Measures

Experienced clinicians discuss the future of acute GvHD treatment, focusing on gaps in patient care and potential therapy options.

Advancements and Promising Directions in Acute GvHD

Insights on treatment strategies and goals for initial chronic GvHD management, including treatment selection rationale and dosing.

Establishing Treatment Objectives for Chronic GvHD: First-Line Strategies

Exploring FDA-approved treatment options for patients with chronic GvHD, with a focus on trial data and adverse effects. 

A Comprehensive Look at Initial Treatment Options for Chronic GvHD

Clinical pearls for community oncologists regarding treatment selection and sequencing in chronic GvHD patients.

Data-Driven Treatment Selection for Patients with Chronic GvHD

Addressing patient monitoring in chronic GvHD, including therapy adjustment indicators and frequency.

Remote Patient Monitoring and Supportive Care Measures in Chronic GvHD

Expert panelists share final thoughts concerning the future of chronic GvHD treatment, highlighting unmet needs, ongoing trials, and promising therapies. 

Enhancing Patient Care in Acute GvHD: Supportive Measures

EP: 1.Understanding Chronic and Acute Graft-Versus-Host Disease Presentation and Diagnosis

EP: 2.Improving Patient Outcomes: Prophylactic Options in Graft-Versus-Host Disease

EP: 3.Optimal First-Line Treatment Approaches for Acute GvHD

EP: 4.Treatment Options in Steroid-Refractory Acute GvHD

EP: 5.Enhancing Patient Care in Acute GvHD: Supportive Measures

EP: 6.Advancements and Promising Directions in Acute GvHD

EP: 7.Establishing Treatment Objectives for Chronic GvHD: First-Line Strategies

EP: 8.A Comprehensive Look at Initial Treatment Options for Chronic GvHD

EP: 9.Data-Driven Treatment Selection for Patients with Chronic GvHD

EP: 10.Remote Patient Monitoring and Supportive Care Measures in Chronic GvHD

EP: 11.The Future of Chronic GvHD Treatment

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