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Opinion|Videos|November 25, 2024

Lung Large Cell Neuroendocrine Carcinoma: A Rare but Aggressive Disease Intro

Author(s)Martin Dietrich, MD, PhD, Soo-Ryum Yang, MD

Panelists discuss how lung large cell neuroendocrine carcinoma (LCNEC) is characterized by its biology, incidence, risk factors, clinical presentation, and prognosis, while addressing the challenges, unmet needs, and the trial data required to guide testing and treatment guidelines for this rare cancer.

Episodes in this series

EP. 1 Lung Large Cell Neuroendocrine Carcinoma: A Rare but Aggressive Disease Intro

EP. 1 Lung Large Cell Neuroendocrine Carcinoma: A Rare but Aggressive Disease Intro

EP. 2 An Overview of the Molecular Characterization of Lung LCNEC

EP. 2 An Overview of the Molecular Characterization of Lung LCNEC

EP. 3 The Pathological Diagnosis of Lung LCNEC

EP. 3 The Pathological Diagnosis of Lung LCNEC

EP. 4 Biomarker Testing Strategies for Lung LCNEC

EP. 4 Biomarker Testing Strategies for Lung LCNEC

EP. 5 Biopsy Best Practices: Diagnosing Lung LCNEC

EP. 5 Biopsy Best Practices: Diagnosing Lung LCNEC

EP. 6 Lung LCNEC Diagnostic Challenges

EP. 6 Lung LCNEC Diagnostic Challenges

EP. 7 A Multidisciplinary Approach to Managing Lung LCNEC

EP. 7 A Multidisciplinary Approach to Managing Lung LCNEC

EP. 8 Lung LCNEC Disease Histology and Prognosis

EP. 8 Lung LCNEC Disease Histology and Prognosis

EP. 9 The Role of DLL3 in LCNEC of the Lung

EP. 9 The Role of DLL3 in LCNEC of the Lung

EP. 10 Insights on the LANCE Pilot Study on Lung LCNEC

EP. 10 Insights on the LANCE Pilot Study on Lung LCNEC

EP. 11 Novel Targeted Therapies for LCNEC of the Lung

EP. 11 Novel Targeted Therapies for LCNEC of the Lung

EP. 12 Overview of Studies of BI 764532 for Lung LCNEC

EP. 12 Overview of Studies of BI 764532 for Lung LCNEC

EP. 13 Insights Into Ongoing Investigational Studies in Lung LCNEC

EP. 13 Insights Into Ongoing Investigational Studies in Lung LCNEC

EP. 14 Potential Next-Generation Therapies for Lung LCNEC

EP. 14 Potential Next-Generation Therapies for Lung LCNEC

EP. 15 Unmet Needs in LCNEC

EP. 15 Unmet Needs in LCNEC

Dr. Dietrich to provide a brief overview of lung LCNEC:

Biology
Incidence
Risk factors
Presentation
Prognosis

Dr. Yang to Dr. Dietrich:

How often do you see these patients in your practice?
What challenges and unmet needs surround lung LCNEC?
What trial data are needed to inform development of guidelines around LCNEC testing and treatment?

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