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The neoadjuvant/adjuvant pembrolizumab and chemotherapy combination was approved by the FDA in October 2023 for use in this patient population.

Perioperative Pembrolizumab Regimen Upholds Survival Benefit in Resectable NSCLC

Zongertinib demonstrated durable efficacy in patients with pretreated advanced HER2-mutant non–small cell lung cancer.

Zongertinib Elicits Durable Responses in Pretreated Advanced HER2-Mutant NSCLC 

Second-line lenvatinib had clinically meaningful efficacy in patients with advanced HCC after progression on atezolizumab plus bevacizumab.

Lenvatinib Shows Efficacy in Advanced HCC Post-Progression on Atezolizumab/Bevacizumab

The phase 3 TROPiCS-04 study missed its primary end point of improved OS with sacituzumab govitecan vs chemotherapy in patients with urothelial cancer.

Sacituzumab Govitecan Does Not Significantly Improve OS in Pretreated Urothelial Carcinoma

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Articles

The FDA awards accelerated approval to encorafenib regimen in BRAF V600E+ CRC, ensartinib wins approval in ALK+ non–small cell lung cancer, and more.

The OncFive: Top Oncology Articles for the Week of 12/15


Gina Mauro is your lead editorial contact for 

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; she is also the on-air correspondent for 

. Prior to joining MJH Life Sciences, she worked at Gannett as a full-time reporter with the Asbury Park Press. Email: gmauro@onclive.com 

 
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 in November 2021 as a senior editor and became the website's managing editor in October 2023. Before arriving at MJH Life Sciences, he spent nearly a decade covering professional and high school sports—including the New Jersey Devils and the NHL from 2016 to 2021—for The Star-Ledger and NJ.com. Email: chryan@onclive.com

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Adding dostarlimab to chemotherapy and niraparib maintenance improved progression-free survival in first-line advanced ovarian cancer.

Addition of Dostarlimab to Chemo and Niraparib Maintenance Boosts PFS in Advanced Ovarian Cancer

 as an assistant editor in October 2022. Leveraging an educational background in the life sciences and prior experience conducting interviews in a university setting, she plays a key role in shaping social media strategy, covering live conferences, and producing multimedia content for both print and digital platforms. Email: 

The addition of pegcrisantaspase to venetoclax may overcome resistance to prior BCL-2 inhibitor–based regimens for patients with relapsed/refractory AML. 

Venetoclax Plus PegC May Overcome Resistance to Prior BCL-2 Inhibitors in R/R AML 

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Updates in the Management of Stage III Non-Small Cell Lung Cancer (NSCLC)

Navigating Neoadjuvant and Perioperative Treatment Strategies in Early Stage NSCLC

Video content above is prompted by the following:

How do you select patients with potentially resectable stage III NSCLC for neoadjuvant vs perioperative therapy?

How do you navigate/translate these data to inform your treatment decisions?

Videos

Led by Sandip P. Patel, MD, key opinion leaders address key updates in treatment strategies and management of stage III NSCLC.

Medical experts discuss a specific case for a patient diagnosed with stage IIIB NSCLC.

Patient with Stage IIIB NSCLC with No Actionable Mutations and PD-L1 TPS 0%

Panelists discuss the utilization of testing and multidisciplinary approaches for testing.

Biomarker Testing and the Multidisciplinary Approach in Early-Stage NSCLC

The panel discusses a variety of clinical trials and the impact on patient treatment in early stage NSCLC.

A variety of treatment options in ES NSCLC are explored by key opinion leaders.

Treatment Considerations for Neoadjuvant and Perioperative Therapy in ES NSCLC 

The panel discusses reassessing for respectability after certain treatments.

Management of Borderline Resectable NSCLC

The panel discusses management of resectable early-stage non–small cell lung cancer.

Management of Resectable Early Stage NSCLC with Actionable Mutations

The panel discusses the factors that go into selecting patients for adjuvant therapy.

Considerations for Combination of Adjuvant Chemotherapy and Targeted Therapy in Resectable ES NSCLC

The panel looks at a second patient case study.

Patient with Unresectable Stage IIIB EGFR-Mutant NSCLC with N2 Bulky Disease 

The panel discusses data necessary for selecting patients with unrespectable non–small cell lung cancer for sequential vs concurrent chemoradiotherapy.

Expert Perspectives on Patient Selection for cCRT and sCRT in Unresectable ES NSCLC

The panel discusses treatment considerations for consolidation durvalumab.

Navigating Neoadjuvant and Perioperative Treatment Strategies in Early Stage NSCLC

EP: 1.Patient with Stage IIIB NSCLC with No Actionable Mutations and PD-L1 TPS 0%

EP: 2.Biomarker Testing and the Multidisciplinary Approach in Early-Stage NSCLC

EP: 3.Navigating Neoadjuvant and Perioperative Treatment Strategies in Early Stage NSCLC

EP: 4.Treatment Considerations for Neoadjuvant and Perioperative Therapy in ES NSCLC

EP: 5.Management of Borderline Resectable NSCLC

EP: 6.Management of Resectable Early Stage NSCLC with Actionable Mutations

EP: 7.Considerations for Combination of Adjuvant Chemotherapy and Targeted Therapy in Resectable ES NSCLC

EP: 8.Patient with Unresectable Stage IIIB EGFR-Mutant NSCLC with N2 Bulky Disease

EP: 9.Expert Perspectives on Patient Selection for cCRT and sCRT in Unresectable ES NSCLC

EP: 10.Treatment Considerations for Consolidation Durvalumab in Unresectable ES NSCLC

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