SABCS 2021 Updates in CDK4/6 Inhibitors in Breast Cancer

EP: 1.Coming Soon: THE TALK: Breast Cancer, A Review of Data from the SABCS 2021 Virtual Meeting

EP: 2.SABCS 2021 Updates in ER+ Breast Cancer

Now Viewing

EP: 3.SABCS 2021 Updates in CDK4/6 Inhibitors in Breast Cancer

EP: 4.SABCS 2021 Updates in Key Clinical Trials for Breast Cancer

Data from the following clinical trials are discussed:

• P1-18-16: First-line aromatase inhibitor + palbociclib with randomized switch to fulvestrant [Faslodex] + palbociclib upon detection of circulating ESR1 mutation in HR+/HER2 metastatic breast cancer patients: Global safety results of PADA-1, a UCBG-GINECO phase 3 trial
• PD2-05: Genomic profiling of PAM50-based intrinsic subtypes in HR+/HER2 advanced breast cancer across the MONALEESA studies
• PD13-03: Ribociclib [Kisqali], everolimus, exemestane [Aromasin] triplet therapy in HR+/HER2 advanced breast cancer after progression on a CDK4/6 inhibitor: Final efficacy, safety, and biomarker results from TRINITI-1
• PD02-04: Molecular plasticity of luminal A breast cancer and response to CDK4/6 inhibition: The biomarker program of the PENELOPE-B trial investigating post-neoadjuvant palbociclib