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J. Bradley Elder, MD, discusses blinded early-safety data from a phase 2b trial of IGV-001 in patients with newly diagnosed glioblastoma.

Dr Elder on the Initial Safety Profile of IGV-001 in Newly Diagnosed Glioblastoma

Rimas V. Lukas, MD, discusses the efficacy of eflornithine plus lomustine in recurrent IDH-mutant anaplastic astrocytoma per 2021 WHO diagnostic criteria.

Dr Lukas on Survival Outcomes With Eflornithine in IDH-Mutant Anaplastic Astrocytoma 

IGV-001, an autologous cell immunotherapy, demonstrated an acceptable safety profile in patients with newly diagnosed glioblastoma.

IGV-001 Showcases Positive Benefit-Risk Profile in Newly Diagnosed Glioblastoma

Paolo Caimi, MD, discusses the rationale behind evaluating LMY-920, a novel BAFF CAR T-cell therapy, in relapsed/refractory non-Hodgkin lymphoma.

Dr Caimi on Early Data for LMY-920 in R/R B-Cell NHL

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Megan Hollasch joined MJH Life Sciences in 2022 following graduation from the University of Massachusetts Amherst with majors in Communication and English, and a specialization in Literature as History. She produces and edits original content for the print publication 

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Jairam Krishnamurthy, MD, FACP, details what to take into consideration when implementing 2024 Breast Cancer NCCN guideline changes into everyday practice. 

Category 1 Recommendation of Ribociclib Plus an AI Represents Huge Advancement in Breast Cancer

 in November 2021 as a senior editor and became the website's managing editor in October 2023. Before arriving at MJH Life Sciences, he spent nearly a decade covering professional and high school sports—including the New Jersey Devils and the NHL from 2016 to 2021—for The Star-Ledger and NJ.com. Email: chryan@onclive.com

Francisco J. Esteva, MD, PhD, highlights various pivotal studies for the treatment of HER2-positive early-stage breast cancer.

Long-Term Findings Solidify Role of HER2-Targeted Therapy in Early HER2+ Breast Cancer

Lu Chen, PhD, an Assistant Professor in the Nuclear Dynamics and Cancer Research Program has received a grant from the NIH to further investigate the role of RNA and the formation of liquid droplet structures within cancer cells.

Fox Chase Cancer Center Researcher Lu Chen Receives $250,000 NIH Grant to Further Investigation of RNA

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Hepatocellular Carcinoma (HCC): Recent Updates and Evolving Treatment Paradigms

Videos

Experts review recent updates in the treatment of HCC and discuss how evidence from clinical trials and real-world settings can be applied to clinical practice to improve patient outcomes.

Experts provide an overview of hepatocellular carcinoma, including the risk factors and prognosis.

Overview of Hepatocellular Carcinoma (HCC)

Key opinion leaders review the process of diagnosing HCC, the role of molecular testing, and associated challenges.

Diagnosing Patients With Hepatocellular Carcinoma

The panel explains the Child-Pugh scoring system and how staging and liver function impact treatment decisions for patients with HCC.

Factoring Stage and Hepatic Function Into Treatment Decision-Making for HCC

Manish Shah, MD, details the role of locoregional therapy in HCC, and Julio Gutierrez, MD, comments on transplant as a curative option.

Treatment Approaches for Patients With Early-Stage HCC

Experts review data from IMbrave050 on the potential role of atezolizumab plus bevacizumab in the adjuvant setting for HCC.

The Role of Adjuvant Therapy in Patients With Early-Stage HCC

Julio Gutierrez, MD, and Ghassan K. Abou-Alfa, MD, discuss the results of the IMbrave150 study investigating atezolizumab plus bevacizumab in the first-line setting for advanced HCC.

Updates in First-Line Systemic Therapy for Advanced HCC: The IMbrave150 Trial

Dr Manish Shah reviews data from the HIMALAYA study on front-line systemic therapy in advanced HCC with tremelimumab plus durvalumab.

Updates in First-Line Systemic Therapy for Advanced HCC: The HIMALAYA Study

Key opinion leaders discuss the sequencing of systemic therapy options for patients with advanced HCC.

Optimal Sequencing in Patients With Advanced HCC

Dr Ghassan K. Abou-Alfa explains the safety profiles of the discussed frontline therapy options for advanced HCC.

Safety Profiles of Available Therapies in Advanced HCC

The panel closes their discussion by highlighting exciting developments on the horizon for the treatment of HCC.

The Future of HCC Treatment

R. Katie Kelley, MD, provides an overview of the first-line systemic treatment options for patients with advanced hepatocellular carcinoma.

First-Line Systemic Treatment Options for Patients With Advanced HCC

Dr R. Katie Kelley shares her thoughts on the four-year updated survival and efficacy data from the phase 3 HIMALAYA trial in patients with advanced hepatocellular carcinoma.

Tremelimumab Plus Durvalumab in Patients With Advanced HCC: The HIMALAYA Study

R. Katie Kelley, MD, discusses updated safety data on tremelimumab plus durvalumab for patients with advanced hepatocellular carcinoma.

Key Safety Outcomes From Updated Analysis of HIMALAYA Trial in Advanced HCC

Dr R. Katie Kelley explains the design and results of the phase 3 CELESTIAL study investigating single-agent cabozantinib for the treatment of advanced hepatocellular carcinoma.

The CELESTIAL Study: Cabozantinib Monotherapy in Advanced HCC Treatment

R. Katie Kelley, MD, comments on the safety and efficacy data from the retrospective analysis of the CELESTIAL study in advanced hepatocellular carcinoma.

Safety and Efficacy Data From the Retrospective Analysis of the CELESTIAL Study in Advanced HCC

Dr R. Katie Kelley highlights other abstracts presented at World GI 2023 and shares what she looks forward to in the future of advanced hepatocellular carcinoma treatment.

Safety and Efficacy Data From the Retrospective Analysis of the CELESTIAL Study in Advanced HCC

EP: 1.Overview of Hepatocellular Carcinoma (HCC)

EP: 2.Diagnosing Patients With Hepatocellular Carcinoma

EP: 3.Factoring Stage and Hepatic Function Into Treatment Decision-Making for HCC

EP: 4.Treatment Approaches for Patients With Early-Stage HCC

EP: 5.The Role of Adjuvant Therapy in Patients With Early-Stage HCC

EP: 6.Updates in First-Line Systemic Therapy for Advanced HCC: The IMbrave150 Trial

EP: 7.Updates in First-Line Systemic Therapy for Advanced HCC: The HIMALAYA Study

EP: 8.Optimal Sequencing in Patients With Advanced HCC

EP: 9.Safety Profiles of Available Therapies in Advanced HCC

EP: 10.The Future of HCC Treatment

EP: 11.First-Line Systemic Treatment Options for Patients With Advanced HCC

EP: 12.Tremelimumab Plus Durvalumab in Patients With Advanced HCC: The HIMALAYA Study

EP: 13.Key Safety Outcomes From Updated Analysis of HIMALAYA Trial in Advanced HCC

EP: 14.The CELESTIAL Study: Cabozantinib Monotherapy in Advanced HCC Treatment

EP: 15.Safety and Efficacy Data From the Retrospective Analysis of the CELESTIAL Study in Advanced HCC

EP: 16.Future of Advanced HCC Treatment

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