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Treatment Strategies in 2L R/R FL: When to Treat vs Observe in Relapsed Disease

Panelists discuss how the treatment approach for relapsed or progressive follicular lymphoma (R/R FL) in the second-line (2L) setting is evolving, focusing on the role of observation vs intervention and the potential impact of ASH 2024 updates, including the inMIND study with tafasitamab and the EPCORE NHL-2 trial with epcoritamab + R2.

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For patients who have disease relapse or POD progression of disease after 1st line therapy, some may benefit from a second period of observation.

When do you treat versus vs observe in the 2L setting?

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