Use of CAR T-cell Therapies for Early Relapse Multiple Myeloma

Panelists discuss the currently available chimeric antigen receptor T-cell therapies for early relapse multiple myeloma, examining their place within the treatment paradigm and how factors such as product type (cilta-cel vs ide-cel) and high-risk features (such as minimal residual disease positivity post induction and extramedullary disease) influence clinical decision-making.

EP: 1.Transplant Eligible, Newly Diagnosed Multiple Myeloma: PERSEUS & CASSIOPEIA Study Updates

EP: 2.Quadruplet Induction Regimen in Newly Diagnosed Multiple Myeloma

EP: 3.Transplant-ineligible Patients with Newly Diagnosed Multiple Myeloma: CEPHEUS, IMROZ, and BENEFIT Studies

EP: 4.MRD Negativity as a Trial Outcome and Its Use in Clinical Practice

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EP: 5.Use of CAR T-cell Therapies for Early Relapse Multiple Myeloma

EP: 6.Considerations for Triplet or Quadruplet Regimens in Transplant-ineligible Patients with Newly Diagnosed Multiple Myeloma

EP: 7.Considerations for Use of CAR T-cell Therapy in Multiple Myeloma

EP: 8.CAR T-cell Therapies for Multiple Myeloma: KarMMa-3 and CARTITUDE-4 Study Updates at IMS 2024

EP: 9.Insights from IMS 2024 on Counseling Patients with Multiple Myeloma about CAR T-cell Therapy and Connecting to Referral Centers

EP: 10.Importance of Early Referral for CAR T-cell Therapy in Multiple Myeloma and Patient Quality of Life

1. Dr Ajai Chari to Dr Rossi: Can you please briefly review the currently available chimeric antigen receptor (CAR) T-cell therapies for early relapse multiple myeloma?
2. Dr Ajai Chari to Dr Rossi (then open to panelists): Where does CAR T-cell therapy currently fall in your treatment paradigm? Does it differ by product (cilta-cel vs ide-cel) or by high-risk features (minimal residual disease positivity post induction, extramedullary disease, etc)?

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