Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond: Guidance and Future Plans
October 21st 2024In this final episode of OncChats: Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond, experts discuss plans for developing guidelines and policies to enhance management of bispecific T-cell engagers across various centers.
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Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond: Prophylactic Measures
October 21st 2024In this episode of OncChats: Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond, experts discuss the need for continued evaluation of prophylactic treatments like tocilizumab and antimicrobial measures for bispecific T-cell engagers.
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Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond: Management Strategies
October 21st 2024In this episode of OncChats: Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond, experts emphasize the need for comprehensive patient education, effective communication, and specific safety protocols to manage patients receiving bispecific T-cell engagers.
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Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond: Awareness of AEs
October 21st 2024In this episode of OncChats: Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond, experts discuss the challenges and strategies in managing bispecific T-cell engagers in the realm of cancer, emphasizing the importance of community and tertiary care collaboration to handle unique AEs like CRS and the need for well-defined protocols.
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Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond: Overview
October 21st 2024In this episode of OncChats: Optimizing the Use of Bispecific Antibodies in Myeloma and Beyond, experts discuss bispecific T-cell engagers, highlighting their effectiveness in treating hematologic malignancies like multiple myeloma, their potential use in solid tumors, and the importance of managing unique toxicities.
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Dr. Saad Usmani discusses the results of the Phase 3 CEPHEUS study, which evaluated the combination of daratumumab with bortezomib/lenalidomide/dexamethasone (D-VRd) in transplant-ineligible or transplant-deferred patients with newly diagnosed multiple myeloma, highlighting its impact on progression-free survival and minimal residual disease negativity.
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Treatment Considerations and Sequencing in Multiple Myeloma
The expert panel concludes their discussion with clinical insights on treatment sequencing and therapeutic decision-making for patients who have relapsed.
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CAR T-Cell Therapy in Multiple Myeloma: Role in the Treatment Landscape
A roundtable discussion on the evolving treatment landscape surrounding CAR T-cell therapy in multiple myeloma, with a focus on future directions and the management of adverse events.
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GPRC5D-Targeting Bispecifics in Multiple Myeloma
The expert panel discusses recent clinical trial data on GPRC5D-targeting bispecific antibodies and how they apply to the multiple myeloma treatment paradigms.
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Adverse Effects Related to Bispecifics in Multiple Myeloma
Comprehensive insights on the adverse effects seen from bispecific antibodies in the treatment of patients with multiple myeloma.
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Step-Up Dosing Practices for Bispecifics in Multiple Myeloma
Multiple myeloma specialists compare step-up dosing practices and provide clinical insights on treating patients with multiple myeloma.
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Real-World Evidence and Selecting Optimal Bispecifics in Multiple Myeloma
Experts on multiple myeloma discuss how real-world evidence informs treatment selection for patients receiving bispecific antibodies.
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Potential Role for CAR T-Cell Therapy in MM at Early Relapse
Krina Patel, MD, reviews data from the CARTITUDE-4 and KarMMa-3 studies and shares perspectives on a potential role for CAR T-cell therapy at early relapse.
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Treatment of Multiple Myeloma at Early Relapse
A panel of expert hematologic-oncologists offer insights on how they treat patients with multiple myeloma at early relapse.
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The Evolving Treatment Paradigm for Transplant Ineligible MM
The expert panel discusses how the standard of care for transplant-ineligible NDMM has evolved and reviews recent updates in this space.
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Safety and Clinical Experience of XPO1 Inhibitors in R/R MM Patients
January 19th 2024Dr. Usmani, MD, MBA, FACP provides insights into Selinexor's safety profile in Relapsed/Refractory Multiple Myeloma (R/R MM), comparing it with other treatments and delve into the ongoing challenges and unmet needs in R/R MM patient care.
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Treatment Strategies in Triple Class Refractory MM Patients
January 19th 2024An expert explores factors influencing the selection of treatment regimens in relapsed, triple class refractory multiple myeloma (MM) patients, with a focus on prophylactic measures for managing adverse events associated with novel agents like Selinexor, bispecific, and CAR-T therapies.
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Role of Transplant and MRD in Newly Diagnosed MM
Amrita Krishnan, MD, and Saad Z. Usmani, MD, MBA, FACP, offer their perspectives on the role of stem cell transplant and MRD testing in patients with newly diagnosed multiple myeloma.
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Advances in the Treatment of High-Risk MM
Clinical insights on the definition of high-risk multiple myeloma and the treatment of patients with high risk disease, including how the results from the IsKia trial might impact practice.
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Highlights from ASH 2023 in Transplant-Eligible NDMM
Experts in multiple myeloma discuss highlights from the ASH 2023 meeting around transplant-eligible NDMM with particular focus on the PERSEUS and GRIFFIN trials and the clinical implications of the results of these studies.
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