Improved Survival Data Seen With Abiraterone as COUGAR Trial Concludes
July 27th 2015Charles J. Ryan, MD, discusses the final survival data for pre-chemotherapy use of abiraterone from the COUGAR-AA-302 study, which demonstrated a median of 35 months for men with castration resistant prostate cancer.
Read More
Amnion/Chorion Wrap Improves Outcomes Following Robot-Assisted Prostatectomy
June 7th 2015Using an allograft made up of dehydrated human amnion/chorion membrane wrapped around the neurovascular bundle (NVB) during nerve-sparing robot-assisted radical prostatectomy improved continence and potency postsurgery, according to results of a small study.
Read More
Progress in Immunotherapy Continues, But Pseudo-Progression Is a Concern
June 5th 2015Interest is high among urologists and medical oncologists with "the explosion of checkpoint blockade inhibition studies" that initially made inroads in melanoma and non-small cell lung cancer, but is also gaining traction in bladder cancer.
Read More
First Effective Adjuvant Treatment Identified in High-Risk Prostate Cancer
May 31st 2015Treatment with an adjuvant combination of docetaxel, androgen deprivation therapy (ADT), and radiation therapy (RT) improved 4-year overall survival rates in patients with high-risk localized prostate cancer, when compared with ADT plus RT alone.
Read More
Physicians Struggle With Antiquated Reimbursement for Next-Generation Testing
May 22nd 2015The growing use of genetic biomarker tests to screen, monitor, diagnose, and treat patients with cancer has the potential to improve outcomes and reduce costs, but payment systems for covering and reimbursing for these tests have fallen behind the times.
Read More
Active Surveillance Protocols Needed for Prostate Cancer
May 16th 2015As the AS strategy gains a foothold among urologists both here in the US and around the world, a study presented at the 110th Annual Scientific Meeting of the American Urological Association suggests that among men in the US, very few are following the stringent protocol for AS that is recommended by major academic institutions.
Read More
Presence of AR-V7 in Stromal, Epithelial Tissue Suggests Role in Carcinogenesis
May 16th 2015The role of androgen receptor variant-7 in patients with early stage prostate cancer is not well characterized but data presented at the 2015 American Urological Association (AUA) Meeting is bringing the discussion into focus.
Read More
Olaparib Nears 90% Response in Molecular Subgroup of mCRPC
April 21st 2015Treatment with olaparib demonstrated a durable overall response rate of 87.5% in a biomarker-defined subgroup of men with pretreated sporadic metastatic castration-resistant prostate cancer in a phase II multi-step adaptive trial.
Read More
Task Force PSA Recommendation Needs Updating, LUGPA President Says
March 16th 2015A United States Preventive Services Task Force recommendation against the use of prostate specific antigen testing needs to be updated, said Gary Kirsh, MD, president of the Large Urology Group Practice Association.
Read More
Making Sense of the Prostate Cancer Screening Debate
March 14th 2015Leonard G. Gomella, MD, told attendees at the 8th Annual IPCC that the decision to screen or not to screen for prostate cancer boiled down to "using common sense, shared decision making, and choosing the right patients to screen."
Read More
PD-1 Agents Vie for Frontline Spot in Melanoma Immunotherapy
February 27th 2015New checkpoint blockade agents that target the PD-1 pathway are moving forward quickly in the melanoma treatment paradigm and likely will become a frontline immunotherapy choice for patients with advanced or metastatic disease, according to Jason J. Luke, MD, FACP, a leading researcher in the field.
Read More
Chemotherapy for CLL Not Yet Obsolete But in Flux as New Agents Gain Ground
February 21st 2015Standard chemotherapy remains part of the treatment paradigm for patients with chronic lymphocytic leukemia but its role is undergoing a major shift as significant advances are being made in novel therapies.
Read More
ASCO Supports ACS Guidelines for Prostate Cancer Survivor Care
February 15th 2015ASCO has endorsed new prostate cancer survivorship care guidelines from the American Cancer Society that provide a structure to help prostate cancer specialists and primary care physicians deliver high quality of care to patients with localized disease.
Read More
Oral Chemotherapy Use Benefits From Safety Self-Assessments
February 9th 2015The Institute for Safe Medication Practices (ISMP) and the Institute for Safe Medication Practices Canada (ISMP Canada) worked collaboratively to create a self-assessment tool to assist oncologists in evaluating safe practices related to medication use.
Read More