Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Cancer Mortality Rate Declined More Steeply in States That Expanded Medicaid Under the Affordable Care Act

Cancer Mortality Rate Declined More Steeply in States That Expanded Medicaid Under the Affordable Care Act

May 14th 2020

The cancer mortality rate declined more in states that expanded Medicaid coverage than those that didn’t following the passage of the Affordable Care Act of 2010, a study found.

Video Conference Visits Effective in Reducing Stress, Anxiety in Caregivers for Patients with Cancer

Video Conference Visits Effective in Reducing Stress, Anxiety in Caregivers for Patients with Cancer

May 14th 2020

The use of video conference technology significantly reduced anxiety and stress among individuals who provide care for an individual with cancer and live more than one hour away from the patient.

Integrated Geriatric Assessment Optimizes Care for Older Adults with Cancer

Integrated Geriatric Assessment Optimizes Care for Older Adults with Cancer

May 13th 2020

Integration of a comprehensive geriatric assessment with geriatrician-led management care improved health-related quality of life, unplanned hospital admissions, and treatment discontinuation among older adults undergoing systemic therapy for their cancer.

Maintenance Therapy with Olaparib Extends Survival in Relapsed, BRCA+ Ovarian Cancer

Maintenance Therapy with Olaparib Extends Survival in Relapsed, BRCA+ Ovarian Cancer

May 13th 2020

Treatment with olaparib in the maintenance setting extended overall survival by 12.9 months in women with platinum-sensitive relapsed ovarian cancer with BRCA1/2 mutations, compared with placebo, according to randomized phase 3 trial results presented during a 2020 ASCO Virtual Scientific Program press briefing.

PARP Inhibitor Trials Revolutionize Frontline Ovarian Cancer

PARP Inhibitor Trials Revolutionize Frontline Ovarian Cancer

May 4th 2020

Transformative clinical trials of PARP inhibitors have revolutionized the frontline treatment paradigm in advanced ovarian cancer.

Innovative Combo Regimens Are Necessary in Heterogeneous Ovarian Cancer Population

Innovative Combo Regimens Are Necessary in Heterogeneous Ovarian Cancer Population

May 3rd 2020

Strategies with PARP inhibitors in ovarian cancer should focus on combination strategies to more effectively treat a heterogeneous patient population.

Optimal Sequencing Remains a Hurdle in Ovarian Cancer Treatment

Optimal Sequencing Remains a Hurdle in Ovarian Cancer Treatment

May 3rd 2020

The surge of treatment options for patients with ovarian cancer poses a daunting challenge as answers for optimal sequencing continue to elude clinicians.

COM701 Shows Early Promise as Monotherapy and Combined With Nivolumab in Advanced Solid Tumors

COM701 Shows Early Promise as Monotherapy and Combined With Nivolumab in Advanced Solid Tumors

April 30th 2020

COM701, a novel, first-in-class immune checkpoint inhibitor, was found to demonstrate encouraging preliminary antitumor activity and good tolerability when used as either a monotherapy and in combination with nivolumab in a number of heavily pretreated patients with advanced or metastatic solid tumors, according to data from a phase 1 trial.

Dr. Algazi on Benefit of Continuous Dabrafenib/Trametinib Dosing in BRAF+ Melanoma

Dr. Algazi on Benefit of Continuous Dabrafenib/Trametinib Dosing in BRAF+ Melanoma

April 30th 2020

Alain Algazi, MD, discusses the benefit of continuous dosing with dabrafenib (Tafinlar) and trametinib (Mekinist) in patients with BRAF mutation–positive advanced melanoma.

RAF-MEK Inhibitor/Defactinib Combo Is Active in KRAS-Mutant Cancers

RAF-MEK Inhibitor/Defactinib Combo Is Active in KRAS-Mutant Cancers

April 30th 2020

The combination of the RAF-MEK inhibitor VS-6766 (CH5126766) and the FAK inhibitor defactinib (VS-6063) elicited early signals of clinical activity in a group of patients with KRAS-mutant advanced cancers.

Cell-Free DNA Detects Adjuvant MRD Positivity and Disease Relapse in NSCLC

Cell-Free DNA Detects Adjuvant MRD Positivity and Disease Relapse in NSCLC

April 29th 2020

Circulating tumor DNA may be a biomarker for the detection of postsurgical minimal residual disease and for determining the clonality of relapsing disease.

cfDNA Assay Shows Predictive Value in Detecting Cancer, Tissue of Origin

cfDNA Assay Shows Predictive Value in Detecting Cancer, Tissue of Origin

April 29th 2020

A cell-free DNA test demonstrated the potential to detect cancer and predict tissue of origin in patients with a suspicion of cancer, according to findings from the Circulating Cell-free Genome Atlas study presented at the 2020 AACR Virtual Annual Meeting I.

TERAVOLT Data Reveal "Unexpectedly High" Mortality in Patients With Thoracic Cancers and COVID-19

TERAVOLT Data Reveal "Unexpectedly High" Mortality in Patients With Thoracic Cancers and COVID-19

April 29th 2020

Early data from TERAVOLT, a global registry collecting characteristics and outcomes of patients with thoracic cancers affected by COVID-19, suggested an unexpectedly high mortality among this patient population.

Blood Test Is Feasible for Early Detection Across Multiple Cancers

Blood Test Is Feasible for Early Detection Across Multiple Cancers

April 29th 2020

A minimally invasive blood test has been found to be feasible to safely detect several types of cancers in patients without a history of malignancies, enabling treatment with curative intent in a subset of individuals.

COVID-19: Practical and Immuno-Oncology Insight in Melanoma and Beyond

COVID-19: Practical and Immuno-Oncology Insight in Melanoma and Beyond

April 29th 2020

Paolo A. Ascierto, MD, discussed lessons he has learned from the COVID-19 crisis both in the melanoma treatment paradigm and in the broader immuno-oncology spectrum.

TIL Therapy Elicits Encouraging Activity in Advanced NSCLC

TIL Therapy Elicits Encouraging Activity in Advanced NSCLC

April 29th 2020

Adoptive cell transfer with tumor-infiltrating lymphocytes was found to be feasible, have a manageable toxicity profile, and expanded in 95% of patients with metastatic non–small cell lung cancer who had disease progression on nivolumab (Opdivo).

Dr. Pusztai on Rationale for the I-SPY 2 Trial With Durvalumab/Olaparib Combo in HER2- Breast Cancer

Dr. Pusztai on Rationale for the I-SPY 2 Trial With Durvalumab/Olaparib Combo in HER2- Breast Cancer

April 29th 2020

Lajos Pusztai, MD, DPhil, discusses the rationale for the phase 2 I-SPY 2 trial examining the addition of durvalumab and olaparib to neoadjuvant paclitaxel in HER2-negative breast cancer.

Positive Safety Profile Reported for Atezolizumab/Axi-Cel Combo in DLBCL

Positive Safety Profile Reported for Atezolizumab/Axi-Cel Combo in DLBCL

April 29th 2020

A manageable safety profile was observed for the combination of atezolizumab and the anti-CD19 chimeric antigen receptor T-cell therapy, axicabtagene ciloleucel, in patients with refractory diffuse large B-cell lymphoma.

Universal Allogeneic CAR T-Cell Product Demonstrates Efficacy in a Cohort of Adult T-ALL

Universal Allogeneic CAR T-Cell Product Demonstrates Efficacy in a Cohort of Adult T-ALL

April 29th 2020

The first-in-clinic universal CAR T-cell therapy TruUCAR GC027 induced promising early response rates and demonstrated a manageable safety profile with no evidence of neurotoxicity events or graft-versus-host disease in adult patients with relapsed/refractory T-cell acute lymphoblastic leukemia.

Adopting Multidisciplinary and Evolving Care Plans Are Essential to Treat Cancer and COVID-19

Adopting Multidisciplinary and Evolving Care Plans Are Essential to Treat Cancer and COVID-19

April 29th 2020

Treating patients with cancer and coronavirus disease 2019 depends upon rapidly changing assessments of the standard of care as well as considerations of comorbidities and life expectancy.

Clinical Factors Predict Deterioration Among Patients With Cancer, COVID-19

Clinical Factors Predict Deterioration Among Patients With Cancer, COVID-19

April 29th 2020

ECOG performance status, cancer type, and type of prior therapy received can predict risk for clinical worsening or death in patients with cancer who contract the coronavirus disease 2019.

Results of a Combined Modality Screening Approach in Women Without Cancer History

Results of a Combined Modality Screening Approach in Women Without Cancer History

April 28th 2020

Nickolas Papadopoulos, PhD, professor of oncology and pathology, Johns Hopkins University School of Medicine, discusses the results of a study which evaluated a combined modality screening approach in women without a history of cancer.

Dr. DiBiase on Data With DM-CHOC-PEN/Radiation in Cancers Involving the CNS

Dr. DiBiase on Data With DM-CHOC-PEN/Radiation in Cancers Involving the CNS

April 28th 2020

Steven J. DiBiase, MD, chair and chief of service for the Julia and Ned Arnold Center for Radiation Oncology, NewYork-Presbyterian Queens, vice chairman and assistant interim professor of radiation oncology, Weill Cornell Medicine, discusses data with 4-demethyl-4 cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) plus radiation in cancers involving the central nervous system (CNS).

Bispecific CD19/CD22 CAR T Cells Active in Pediatric Relapsed ALL

Bispecific CD19/CD22 CAR T Cells Active in Pediatric Relapsed ALL

April 28th 2020

Treatment with CD19/22 chimeric antigen receptor CAR T cells induced a promising response in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia.

Novel Innate Immune Activator Boosts PD-1 Inhibition Responses in mTNBC

Novel Innate Immune Activator Boosts PD-1 Inhibition Responses in mTNBC

April 28th 2020

The addition of the novel innate immune activator, Imprime PGG, to checkpoint inhibition with pembrolizumab showed pronounced clinical benefit in patients with previously treated metastatic triple-negative breast cancer.

Adding Durvalumab/Olaparib to Neoadjuvant Chemo Improves pCR in High-Risk HER2-Negative Breast Cancer

Adding Durvalumab/Olaparib to Neoadjuvant Chemo Improves pCR in High-Risk HER2-Negative Breast Cancer

April 28th 2020

The addition of durvalumab (Imfinzi) and olaparib (Lynparza) to neoadjuvant paclitaxel was found to improve pathologic complete response rates compared with paclitaxel alone in patients with high-risk, HER2-negative stage II/III breast cancer.

Poziotinib Shows Mixed Findings in Exon 20-Mutant NSCLC

Poziotinib Shows Mixed Findings in Exon 20-Mutant NSCLC

April 28th 2020

Patients with pretreated non–small cell lung cancer and EGFR exon 20 insertions demonstrated a 68.7% disease control rate while on poziotinib systemic therapy.

Capmatinib Shows Clinical Meaningful Activity and Intracranial Responses in MET Exon 14+ NSCLC

Capmatinib Shows Clinical Meaningful Activity and Intracranial Responses in MET Exon 14+ NSCLC

April 28th 2020

Results from the GEOMETRY mono-1 study demonstrated antitumor efficacy of and deep and durable responses with capmatinib in 97 patients with advanced non–small cell lung cancer who harbor MET exon 14 mutations.