Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

New Agents Show Promise in Gastric Cancer

New Agents Show Promise in Gastric Cancer

July 3rd 2015

Josep Tabernero, MD, PhD, summarized novel agents that are currently under exploration for patients with gastric cancer.

Dr. Eric Van Cutsem on Regorafenib for Metastatic Colorectal Cancer

Dr. Eric Van Cutsem on Regorafenib for Metastatic Colorectal Cancer

July 3rd 2015

Eric Van Cutsem, MD, PhD, of University Hospitals Gasthuisberg/Leuven, Leuven, Belgium, discusses the safety profile of the phase III B CONSIGN study, which looked at regorafenib in patients with previously treated metastatic colorectal cancer (mCRC).

Hepatitis C "Revolution" May Transform Liver Cancer Outcomes

Hepatitis C "Revolution" May Transform Liver Cancer Outcomes

July 2nd 2015

Novel agents that target the replication of the hepatitis C virus are poised to have a far-reaching impact on the prevention and recurrence of hepatocellular carcinoma and have shown the ability to reverse liver fibrosis, including cirrhosis in patients with end-stage HCC.

IMM-101 Active, Maintains QoL in Patients with Metastatic Pancreatic Cancer

IMM-101 Active, Maintains QoL in Patients with Metastatic Pancreatic Cancer

July 2nd 2015

Investigators reported a clinically meaningful extension of overall survival with IMM-101 plus gemcitabine in patients with metastatic pancreatic cancer.

Dr. Dirk Arnold on Sirflox Study Results in Colorectal Cancer

Dr. Dirk Arnold on Sirflox Study Results in Colorectal Cancer

July 2nd 2015

Dirk Arnold, MD, director of the Department of Medical Oncology at Klinik für Tumorbiologie, Freiburg, Germany, discusses the phase III Sirflox study, which looked at selective internal radiation therapy (SIRT) using Yttrium-90 (Y-90) resin microspheres for the treatment of metastatic colorectal cancer.

Dr. Philip on Evofosfamide for Pancreatic Cancer

Dr. Philip on Evofosfamide for Pancreatic Cancer

July 2nd 2015

Philip Philip MD, PhD, professor of oncology at Karmanos Cancer Center, Wayne State University School of Medicine, discusses the use of the investigational drug evofosfamide for pancreatic cancer.

Dr. Hendifar on PEGPH20 Survival Impact in High Hyaluronan Pancreatic Cancer

Dr. Hendifar on PEGPH20 Survival Impact in High Hyaluronan Pancreatic Cancer

July 1st 2015

Andrew Hendifar, MD, MPH, Assistant Professor of Medicine at Cedars Sinai Medical Center and the David Geffen School of Medicine, discusses the use of a PEGylated form of rHuPH20 (PEGPH20) added to nab-paclitaxel/gemcitabine for pancreatic cancer patients with high levels of hyaluronan (HA).

Low BMI Prognostic for Worse Survival in Colorectal Cancer

Low BMI Prognostic for Worse Survival in Colorectal Cancer

July 1st 2015

Results from a pooled dataset of more than 6000 patients with metastatic colorectal cancer found an association between low body mass index and a worse median overall survival with first-line bevacizumab and chemotherapy, suggesting that low BMI could be a prognostic factor for worse outcomes.

Dr. Zafar on Low BMI Impact on Colorectal Cancer Survival

Dr. Zafar on Low BMI Impact on Colorectal Cancer Survival

July 1st 2015

S. Yousuf Zafar, MD, Associate Professor of Medicine at Duke Cancer Institute, discusses the potential link between low body mass index (BMI) and survival outcomes in metastatic colorectal cancer.

 Martin Barrett on Intravenous Versus Subcutaneous Rituximab

Martin Barrett on Intravenous Versus Subcutaneous Rituximab

June 20th 2015

Martin Barrett, PhD, Clinical Scientist at Hoffmann-La Roche, discusses a study which compared intravenous (IV) rituximab to subcutaneous rituximab in non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL).

CAR-Modified T-Cell Therapy Shows Durable Response in Non-Hodgkin Lymphoma

CAR-Modified T-Cell Therapy Shows Durable Response in Non-Hodgkin Lymphoma

June 20th 2015

Infusions of CTL019 achieved durable responses and showed an acceptable safety profile in heavily pretreated patients with CD19-positive non-Hodgkin lymphoma.

Venetoclax Combination Shows Antitumor Activity in Advanced Myeloma

Venetoclax Combination Shows Antitumor Activity in Advanced Myeloma

June 20th 2015

A three-drug combination comprising the novel Bcl-2 inhibitor venetoclax, bortezomib, and dexamethasone demonstrated a clinical benefit in heavily pretreated patients with relapsed/refractory multiple myeloma.

Lenalidomide Highly Effective in Early Phase CNS Lymphoma Study

Lenalidomide Highly Effective in Early Phase CNS Lymphoma Study

June 20th 2015

Lenalidomide in combination with rituximab and as maintenance monotherapy is highly active in patients with relapsed/refractory central nervous system non-Hodgkin lymphoma.

Dr. Atanasio on Ibrutinib and Obinuzutumab Combination in CLL/SLL

Dr. Atanasio on Ibrutinib and Obinuzutumab Combination in CLL/SLL

June 20th 2015

Carolina Moreno Atanasio, MD, University of Barcelona, discusses an ongoing phase III study comparing ibrutinib and obinutuzumab with chlorambucil and obinutuzumab in treatment-naïve patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

Dr. Wiestner Discusses Findings From the Phase III HELIOS Trial

Dr. Wiestner Discusses Findings From the Phase III HELIOS Trial

June 19th 2015

Adrian Wiestner, MD, PhD, National Institutes of Health, National Heart, Lung, and Blood Services, discusses findings from the phase III HELIOS trial, which explored the addition of ibrutinib to bendamustine and rituximab for patients with relapsed/refractory chronic lymphocytic leukemia.

Ibrutinib, Ublituximab, TGR-1202 Triplet Active in Relapsed B-Cell Malignancies

Ibrutinib, Ublituximab, TGR-1202 Triplet Active in Relapsed B-Cell Malignancies

June 19th 2015

A chemotherapy-free combination of the anti-CD20 antibody ublituximab, ibrutinib, and the PI3K delta inhibitor TGR-1202 demonstrated robust clinical activity in patients with relapsed/refractory chronic lymphocytic leukemia or B-cell non-Hodgkin lymphoma.

PI3Kδ and JAK1 Inhibitors Show Promise in Advanced Hodgkin Lymphoma

PI3Kδ and JAK1 Inhibitors Show Promise in Advanced Hodgkin Lymphoma

June 19th 2015

The PI3Kδ inhibitor INCB040093 alone or in combination with the JAK1 inhibitor INCB039110 showed early promise in relapsed/refractory classical Hodgkin lymphoma.

Dr. O'Brien Discusses Ibrutinib and Idelalisib in CLL

Dr. O'Brien Discusses Ibrutinib and Idelalisib in CLL

June 19th 2015

Susan M. O'Brien, MD, associate director, Clinical Science Medical Director of the Sue and Ralph Stern Center for Cancer Clinical Trials and Research, Chao Family Comprehensive Cancer Center, University of California at Irvine, discusses the use of ibrutinib and idealisib in chronic lymphocytic leukemia (CLL).

Nivolumab Elicits Durable Responses in Lymphoma

Nivolumab Elicits Durable Responses in Lymphoma

June 19th 2015

Nivolumab continued to show high activity and a good safety profile after more than a year of follow-up in heavily pretreated patients with relapsed or refractory lymphoid malignancies or those with classical Hodgkin lymphoma.

Rituximab, Thiotepa, and Chemo Combo Improves Outcomes in Primary CNS Lymphoma

Rituximab, Thiotepa, and Chemo Combo Improves Outcomes in Primary CNS Lymphoma

June 18th 2015

The MATRIX regimen, comprised of a methotrexate/cytarabine backbone plus thiotepa and rituximab, improved outcomes in patients with primary CNS lymphoma.

SYK Inhibitor TAK-659 Shows Promising Results in Lymphoid Malignancies

SYK Inhibitor TAK-659 Shows Promising Results in Lymphoid Malignancies

June 18th 2015

TAK-659, an inhibitor of spleen tyrosine kinase, showed early signs of antitumor activity in patients with lymphoma, with two expansion arms planned for patients with diffuse large B-cell lymphoma and chronic lymphocytic leukemia.

Dr. Uldrick on Rituximab Plus Liposomal Doxorubicin in HIV-Infected Patients With KSHV-MCD

Dr. Uldrick on Rituximab Plus Liposomal Doxorubicin in HIV-Infected Patients With KSHV-MCD

June 18th 2015

Thomas S. Uldrick, MD, staff clinician, HIV and AIDS Malignancy Branch, Center for Cancer Research at the National Institutes of Health, discusses long-term data from a study examining rituximab plus liposomal doxorubicin in HIV-infected patients with Kaposi sarcoma (KS) herpes virus-associated multicentric Castleman disease.

Interim FDG-PET Scans Enable Response-Adapted Therapy in Hodgkin Lymphoma

Interim FDG-PET Scans Enable Response-Adapted Therapy in Hodgkin Lymphoma

June 18th 2015

Interim PET-CT scanning was successfully used to adapt treatment regimens in patients with advanced classical Hodgkin lymphoma.

Dr. Adrian Wiestner on RESONATE II Trial

Dr. Adrian Wiestner on RESONATE II Trial

June 17th 2015

Adrian Wiestner, MD, PhD, Senior Investigator, Laboratory of Lymphoid Malignancies, National Institutes of Health, National Heart, Lung, and Blood Services discusses the findings of the RESONATE II trial, which looked at chlorambucil versus ibrutinib as first-line therapy in patients older than 65 with chronic lymphocytic leukemia (CLL).

Lenvatinib Plus Everolimus Improves Survival in mRCC

Lenvatinib Plus Everolimus Improves Survival in mRCC

June 5th 2015

The combination of lenvatinib and everolimus more than doubled progression-free survival and extended overall survival by 10.1 months compared with everolimus alone as a second-line treatment for patients with metastatic renal cell carcinoma.

Dr. Van Tine on Trabectedin for Leiomyosarcoma and Liposarcoma

Dr. Van Tine on Trabectedin for Leiomyosarcoma and Liposarcoma

June 3rd 2015

Brian A. Van Tine, MD, PhD, Assistant Professor Department of Medicine Siteman Cancer Center, Washington University School of Medicine, discusses trabectedin (Yondelis) for the treatment of soft tissue sarcomas.

Carfilzomib Tops Bortezomib in Relapsed Myeloma

Carfilzomib Tops Bortezomib in Relapsed Myeloma

June 3rd 2015

Progression-free survival in relapsed myeloma doubled among patients treated with carfilzomib, rather than bortezomib, in combination with dexamethasone, a randomized trial showed.

Dr. Brufsky on Anastrozole Versus Tamoxifen in DCIS

Dr. Brufsky on Anastrozole Versus Tamoxifen in DCIS

June 3rd 2015

Adam M. Brufsky, MD, PhD, professor of Medicine, associate chief, Division of Hematology/Oncology, co-director, Comprehensive Breast Cancer Center, associate director, Clinical Investigation, University of Pittsburgh, compares the use of anastrozole to tamoxifen in patients with ductal carcinoma in situ (DCIS).

Dr. Cristofanilli on the PALOMA3 Trial for Breast Cancer

Dr. Cristofanilli on the PALOMA3 Trial for Breast Cancer

June 3rd 2015

Massimo Cristofanilli, MD, Jefferson University Physician, professor, director, Breast Care Center, discusses the PALOMA3 trial.

PD-1/PD-L1 Inhibitors Safe, Effective in Advanced Ovarian Cancer

PD-1/PD-L1 Inhibitors Safe, Effective in Advanced Ovarian Cancer

June 3rd 2015

Monoclonal antibodies against PD-1 and PD-L1 have demonstrated encouraging signs of antitumor activity for patients with pretreated advanced ovarian cancer.