Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Dr. Garcia-Manero on Deferasirox in Iron Chelation Therapy for MDS

Dr. Garcia-Manero on Deferasirox in Iron Chelation Therapy for MDS

May 7th 2015

Guillermo Garcia-Manero, MD, chief, Section of Myelodysplastic Syndromes, deputy chair, Translational Research, professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses deferasirox (Exjade) in iron chelation therapy for patients with myelodysplastic syndromes (MDS).

Eltrombopag Effectively Treats Cytopenias in MDS

Eltrombopag Effectively Treats Cytopenias in MDS

May 2nd 2015

Treatment with the thrombopoietin receptor agonist eltrombopag significantly improved cytopenias and was well-tolerated in patients with low to intermediate-2 risk myelodysplastic syndromes.

Somatic Mutations Could Predict Response to Hypomethylating Agents in MDS

Somatic Mutations Could Predict Response to Hypomethylating Agents in MDS

May 2nd 2015

A biomarker model that incorporates the mutational status of multiple somatic genes could be used to predict response to hypomethylating agents for patients with myelodysplastic syndromes.

IPSS Risk and EPO Levels Predict Response to ESAs in MDS

IPSS Risk and EPO Levels Predict Response to ESAs in MDS

May 2nd 2015

Serum erythropoietin levels and risk by IPSS were predictive of response to erythropoiesis-stimulating agents in patients with myelodysplastic syndromes.

Dr. Gail Roboz on Molecular Mutations in MDS

Dr. Gail Roboz on Molecular Mutations in MDS

May 2nd 2015

Gail J. Roboz, MD, associate professor of Medicine, director, Leukemia Program, Weill Medical College of Cornell University, New York-Presbyterian Hospital, discusses the growing field of molecular mutations in myelodysplastic syndromes (MDS).

Dr. Zeidan on Subsequent MDS in Prostate Cancer Patients After Radiotherapy

Dr. Zeidan on Subsequent MDS in Prostate Cancer Patients After Radiotherapy

May 2nd 2015

Amer Zeidan, MBBS, MHS, assistant professor of Medicine, Hematology, Yale Cancer Center, discusses a population-based study of subsequent myelodysplastic syndromes (MDS) in prostate cancer patients after radiotherapy.

T-Cell Depleted Allografts Lessen GVHD in MDS

T-Cell Depleted Allografts Lessen GVHD in MDS

May 1st 2015

Treatment with T-cell depleted transplantation was associated with a lower incidence of acute graft versus host disease (GVHD) and a very low incidence of chronic GVHD compared with unmodified allografts in patients with advanced myelodysplastic syndrome.

Lenalidomide Improves Quality of Life in Non-Del5q MDS

Lenalidomide Improves Quality of Life in Non-Del5q MDS

May 1st 2015

Treatment with lenalidomide (Revlimid) versus placebo improved health-related quality of life (HRQoL) after 24 weeks for patients with myelodysplastic syndromes.

Supportive Care Remains Backbone of Treatment in MDS

Supportive Care Remains Backbone of Treatment in MDS

May 1st 2015

Treatment strategies for patients with myelodysplastic syndromes are built upon a foundation of supportive care, which consists of transfusions, iron chelation, and growth factor therapy.

Sara Tinsley Discusses Quality of Life in Patients with High-Risk MDS

Sara Tinsley Discusses Quality of Life in Patients with High-Risk MDS

May 1st 2015

Sara M. Tinsley, MS, PhD, ARNP, AOCN, nurse practitioner, malignant hematology, Moffitt Cancer Center, discusses a study that examined quality of life in patients with high-risk myelodysplastic syndromes (MDS).

Dr. Komrokji on Risk Stratification of Therapy-Related MDS

Dr. Komrokji on Risk Stratification of Therapy-Related MDS

May 1st 2015

Rami S. Komrokji, MD, clinical director, Department of Malignant Hematology, H. Lee Moffitt Cancer Center, discusses a study that examined risk stratification of therapy-related MDS.

Novel Agents Sotatercept and Rigosertib Show Potential in MDS

Novel Agents Sotatercept and Rigosertib Show Potential in MDS

April 30th 2015

OncLive spoke with Guillermo Garcia-Manero, MD, regarding the significance of sotatercept and rigosertib and their potential as therapies in MDS.

HLA-Matched Transplantation Improves OS in High-Risk MDS

HLA-Matched Transplantation Improves OS in High-Risk MDS

April 30th 2015

HLA-matched allogeneic hematopoietic stem cell transplantation was associated with more than a doubling in 4-year overall survival rates for patients with intermediate-2 or high-risk myelodysplastic syndromes.

Dr. Scott on Connect MDS and AML: A Disease Registry

Dr. Scott on Connect MDS and AML: A Disease Registry

April 30th 2015

Bart L. Scott, assistant member, clinical research division, Fred Hutchinson Cancer Research Center, discusses a new registry that will collect data from patients with MDS.

Dr. Garcia-Manero on Rigosertib in Patients with High-Risk MDS After Failure of Hypomethylating Agents

Dr. Garcia-Manero on Rigosertib in Patients with High-Risk MDS After Failure of Hypomethylating Agents

April 30th 2015

Guillermo Garcia-Manero, MD, chief, Section of Myelodysplastic Syndromes, deputy chair, Translational Research, professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses the multikinase inhibitor rigosertib in patients with MDS who have failed hypomethylating agents.

Sotatercept Effectively Treats Anemia in MDS and Non-Proliferative CMML

Sotatercept Effectively Treats Anemia in MDS and Non-Proliferative CMML

April 30th 2015

The first-in-class activin receptor antagonist sotatercept stimulated erythropoiesis in nearly half of patients with MDS and non-proliferative CMML following failure on erythropoiesis-stimulating agents.

Supportive Care Is Key in MDS Treatment

Supportive Care Is Key in MDS Treatment

April 28th 2015

Interview with Thomas Prebet MD, PhD, in advance of the 2015 International MDS Symposium, on topics related to supportive care in MDS and iron chelation therapy.

Oncology Nurses Poised to Make a Difference in Managing “Silent” Portal Vein Thrombosis

Oncology Nurses Poised to Make a Difference in Managing “Silent” Portal Vein Thrombosis

April 28th 2015

Portal vein thrombosis is a dangerous and often overlooked side effect of certain gastrointestinal malignancies such as liver and pancreatic cancer, that oncology nurses need to be more proactive in managing.

Dr. Camidge on MET as a Target in Lung Cancer

Dr. Camidge on MET as a Target in Lung Cancer

April 23rd 2015

D. Ross Camidge, MD, director, Thoracic Oncology Clinical Program, program director, Thoracic Oncology Clinical and Translational Research Fellowship, University of Colorado Denver, discusses MET and if it is still a relevant target in lung cancer.

Dr. Bast on Earlier Detection of Ovarian Cancer

Dr. Bast on Earlier Detection of Ovarian Cancer

April 22nd 2015

Robert C. Bast, Jr., MD, vice president, Translational Research, The University of Texas MD Anderson Cancer Center, discusses a study that could help in early detection of ovarian cancer before CA-125 rises in patients.

Olaparib Proves Versatile When Paired With AKT Inhibitor

Olaparib Proves Versatile When Paired With AKT Inhibitor

April 22nd 2015

The combination of olaparib with the novel AKT-targeting agent AZD5363 generated responses in a variety of tumor types among patients with and without BRCA1/2 mutations, demonstrating that a simultaneous attack on the two pathways is a safe and potentially versatile strategy.

Dr. Herbst on Nivolumab for NSCLC

Dr. Herbst on Nivolumab for NSCLC

April 22nd 2015

Roy S. Herbst, MD, PhD, professor, Yale Cancer Center, chief of medical oncology, Smilow Cancer Hospital at Yale-New Haven, discuses the impact of the FDA's approval of nivolumab's for the treatment of squamous non-small cell lung cancer.

Olaparib Plus BKM120 Combo Gains Traction in Breast and Ovarian Cancers

Olaparib Plus BKM120 Combo Gains Traction in Breast and Ovarian Cancers

April 21st 2015

A two-pronged strategy combining the PARP inhibitor olaparib and the PI3K inhibitor BKM120 proved to be a safe and clinically beneficial regimen for women with triple-negative breast cancer and for patients with high-grade serous ovarian cancer.

Dr. Mittendorf on Nelipepimut-S in Breast Cancer

Dr. Mittendorf on Nelipepimut-S in Breast Cancer

April 21st 2015

Elizabeth A. Mittendorf, MD, PhD, associate professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, discusses nelipepimut-S (NeuVax) and a proposed trial for patients with ductal carcinoma in situ (DCIS).

Olaparib Nears 90% Response in Molecular Subgroup of mCRPC

Olaparib Nears 90% Response in Molecular Subgroup of mCRPC

April 21st 2015

Treatment with olaparib demonstrated a durable overall response rate of 87.5% in a biomarker-defined subgroup of men with pretreated sporadic metastatic castration-resistant prostate cancer in a phase II multi-step adaptive trial.

Dr. Welsh on New Understanding of Regulating PD-L1 Expression

Dr. Welsh on New Understanding of Regulating PD-L1 Expression

April 21st 2015

James Welsh, MD, associate professor of Radiation Oncology, The University of Texas MD Anderson Cancer Center, discusses a study that examined the regulation of PD-L1 and how it may open up more treatment options for patients with non-small cell lung cancer.

HPV Vaccine May Benefit Women Previously Exposed to the Virus

HPV Vaccine May Benefit Women Previously Exposed to the Virus

April 21st 2015

HPV vaccination may offer protection against HPV-related cancers across multiple tumor sites in women aged 18-25 who had been previously exposed to HPV.

Adding Nivolumab to Frontline Ipilimumab Improves PFS by 60% in Melanoma

Adding Nivolumab to Frontline Ipilimumab Improves PFS by 60% in Melanoma

April 20th 2015

Frontline immunotherapy with nivolumab plus ipilimumab delayed disease progression by 60% compared with ipilimumab alone in patients with advanced melanoma.

Dr. Hodi on Nivolumab in Combination With Ipilimumab for Advanced Melanoma

Dr. Hodi on Nivolumab in Combination With Ipilimumab for Advanced Melanoma

April 20th 2015

F. Stephen Hodi, MD, discusses the results of a trial presented at the 2015 AACR Annual Meeting.

Anti-PD-L1 Agent MPDL3280A Shows Durable Responses in TNBC

Anti-PD-L1 Agent MPDL3280A Shows Durable Responses in TNBC

April 20th 2015

The PD-L1 inhibitor MPDL3280A demonstrated a 19% objective response rate (ORR) with 75% of responses ongoing in pretreated patients with metastatic triple-negative breast cancer.