Vijayakrishna Gadi, MD, PhD, sets the stage for a discussion around HER2-directed ADCs in the solid tumor space.
EP. 1: Assessing HER2 Status Across Tumor Types
Dr Gadi leads a discussion surrounding HER2 mutation and overexpression across various cancer types.
EP. 2: ADCs Targeting HER2+ Breast Cancer
Dr Gadi introduces treatment and trial data targeting care for patients diagnosed with HER2+ breast cancer.
EP. 3: ADCs Targeting HER2+ Gynecologic Cancers
Dr Campos discusses the potential for T-DXd in other gynecologic cancers and offers an overview of results from the DESTINY-PanTumor02 trial.
EP. 4: Emerging Data from ASCO 2024 in HER2-low: DESTINY-Breast06
Dr Gadi leads a discussion on recent data on the treatment of HER2-low tumors, including ASCO updates on the DESTINY-Breast06 trial.
EP. 5: ADCs Targeting GI Cancers
Dr Parikh discusses the history of ADCs for treating GI cancers with a focus on the data for T-DXd and its role in treating these cancers.
EP. 6: ADCs Targeting HER2+ Lung Cancer
Dr Garon shares insights on the role of ADCs for the treatment of HER2+ lung cancer.
EP. 7: Impact of ADCs on Brain Metastases
A panel of experts discuss where HER2-directed ADCs antibody-drug conjugates fit into the overall treatment paradigm.
EP. 8: ADCs Targeting HER2+ GU Cancers
A panel of experts discuss if there is a role for HER2-directed ADCs antibody-drug conjugates in GU genitourinary cancers
EP. 9: Overcoming Challenges of Testing for HER2-low Across Solid Tumor Types
A panel of experts discuss the challenges of testing for HER2-low access solid tumor types.
EP. 10: The Potential Role for HER2-Targeted ADCs in Earlier Treatment Lines
Vijayakrishna Gadi, MD, PhD, discusses the role of antibody-drug conjugates in a curative setting.
EP. 11: Managing ILD and Pneumonitis Risk From ADCs
Vijayakrishna Gadi, MD, PhD, discusses the risk of ILD and pneumonitis from ADCs.
EP. 12: Managing Toxicities in Short- and Long-Term Treatment with ADCs
Vijayakrishna Gadi, MD, PhD, discusses short-term and long-term treatments with ADCs.
EP. 13: Managing Hematologic AEs Associated with ADC Treatments
A panel of experts discuss hematologic adverse events associated with antibody-drug conjugate therapies.
EP. 14: Management of Emetogenicity of Antibody-Drug Conjugates
Experts provide clinical insights on the management of emetogenicity in patients receiving antibody-drug conjugates.
EP. 15: ADC Sequencing
Expert clinicians offer strategic guidance on optimal sequencing of antibody-drug conjugates (ADCs) in treatment protocols.
EP. 16: Emerging ADCs in Development
Key opinion leaders examine promising antibody-drug conjugates (ADCs) in the pharmaceutical development pipeline.
EP. 17: Insights on T-DXd Approval as Tumor-Agnostic HER2-Directed Therapy
Ronan Kelly, MD, MBA, offers insights on trastuzumab deruxtecan approval as tumor-agnostic HER2-directed therapy.
EP. 18: The Future for HER2-Directed ADCs
Ronan Kelly, MD, MBA, offers insights on the future for HER2-directed antibody-drug conjugates.
EP. 19: Key Takeaways and Closing Thoughts on ADCs
Experts discuss key takeaways and closing thoughts on antibody-drug conjugates (ADCs) in cancer treatment.
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